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The diagnosis of neoplastic and non-neoplastic disorders of bone and soft tissue requires careful correlation of clinical, radiographic and pathologic findings.

Because bone and soft tissue tumors are rare and the diagnosis of a bone or soft tissue sarcoma often leads to a combination of chemotherapy or radiotherapy and radical surgery, a multidisciplinary approach to diagnosis and treatment is essential. A variety of pseudosarcomatous and reactive lesions of bone and soft tissue are often mistaken for sarcomas, leading to unnecessary surgery or adjuvant therapy.

The members of the University of Florida's Bone and Soft Tissue Pathology Unit (John D. Reith, M.D., unit director, and Jackie Knapik, M.D.) incorporate radiographic and clinical data with histologic, immunohistochemical and molecular diagnostic analysis to accurately diagnose a variety of neoplastic and non-neoplastic bone and soft tissue disorders. When necessary, cases are discussed at a multidisciplinary conference that is attended by radiologists and orthopaedic surgeons with expertise in the diagnosis and treatment of musculoskeletal disorders.

Bone & Soft Tissue Pathology