William E Winter

William E Winter, M.D.

Emeritus Professor

Department: MD-PATHOLOGY-GENERAL
Business Phone: (352) 294-5540
Business Email: wwinter@ufl.edu

About William E Winter

A native of San Francisco, California, Dr. William E. Winter attended Santa Clara University as an undergraduate majoring in chemistry. He attained his medical degree at Loyola University of Chicago in Maywood, Illinois. Thereafter, Dr. Winter trained in pediatrics at the University of Kentucky followed by training in pediatric endocrinology at the University of Florida under Dr. Arlan Rosenbloom and Dr. Noel Maclaren. Dr. Winter held medical boards in pediatrics, pediatric endocrinology and chemical pathology. He also was boarded by the American Board of Clinical Chemistry (ABCC). Dr. Winter is a fellow of the College of American Pathologists (FCAP) and is a fellow of the Association for Diagnostics and Laboratory Medicine (FADLM). Dr. Winter was professor of Pathology, Immunology & Laboratory Medicine, Pediatrics, and Molecular Genetics & Microbiology at the University of Florida until his retirement in 2023 when he was appointed as an Emeritus Professor. Between 1993 and 2006 he served as Medical Director for clinical chemistry at UF Health Shands Hospital in Gainesville, Florida. Dr. Winter directed the pathology residency training program for a total of 10 years through 2004. In addition to his duties as a clinical chemist, he directed the 2nd year medical student pathology course between 2004 and 2012. Following the medical student curriculum revision of 2012, Dr. Winter founded the following courses: the respiratory system, the cardiovascular system, kidney and the urinary tract, gastroenterology and hepatology, dermatology and the musculoskeletal system. and hematology. He taught in the Foundations of Medicine course, Fundamentals of Microbiology and Immunology, Introduction to Cancer Biology and Clinical Oncology, the Pain and Addition intensive, and Endocrinology and Reproduction. Between 2004 and 2020, Dr. Winter served as the course director for Dental Pathology in the College of Dentistry. Dr. Winter’s final clinical assignments were as the medical director for point-of-care testing and as medical director for phlebotomy (Clinical Laboratory Support Services). Dr. Winter was an NIH-funded independent investigator from 2000 until his retirement. His final NIH funding was as Principle Investigator for the Type 1 Diabetes TrialNet Islet Cell Autoantibody Core Laboratory (https://www.trialnet.org/), The Environmental Determinants of Diabetes in the Young (TEDDY) Core Laboratory (that included the Islet Autoantibody Standardization Program (https://teddy.epi.usf.edu/), and the Rare and Atypical Diabetes Network (RADIANT) Central Laboratory (https://www.atypicaldiabetesnetwork.org/).

Accomplishments

Basic Science Teacher of the Year
2014 · Class of 2014, University of Florida
Golden Apple Award for Pathology
2014 · Class of 2014, University of Florida
Exemplary Teacher Award
2013-2014 · University of Florida

Teaching Profile

Courses Taught
2014-2017,2020-2021
BMS6635 Derm and Msk
2013-2014,2019-2022
BMS6031 Foundations of Med
2014,2019-2022
BMS6634 GI and Hepatology
2014-2018,2020-2023
BMS6638C Kidney & Urinary Tract
2009-2023
DEN6350 General Pathology
2013,2015-2020,2020-2023
BMS6633 The Cv System
2014-2018,2020-2023
BMS6631 Hematology
2018,2020-2023
BMS6300 Fund Micro and Immuno
2020-2023
BMS6632 Endo and Reproduction
2013-2018
MDT7530 Elect Top/Pathology
2015
BMS6642 The Resp Sys Hlth
2015,2021-2023
GMS6140 Principles of Immunology
2011-2012,2014
DEN6416C Basic Sciences Rev
2009-2013
MEL7936 Elect Top/Pathology
2009-2012
BMS6601C Gen Pathol and Immunol
2011-2012
BMS6602C Sys Pathol/Lab Med
2007
DEN6350C Disorders Body System
Teaching Philosophy
Dr. Winter is dedicated to teaching medical students, residents, fellows and colleagues basic concepts of “problem solving.” Knowledge of basic and clinical sciences provides a set of tools to accomplish “problem solving.” The more knowledge one has, the more “tools” that one has in their “tool box.” The challenge then becomes using these tools, together with the patient’s history, physical examination, imaging studies and laboratory testing, to arrive at a single diagnosis or set of possible diagnoses. The wonder of laboratory medicine is that laboratory medicine is applied, real-world, biochemistry, physiology and molecular biology. Therapy is then directed at aiding the patient’s own physiology in healing. Sometimes, invasive diagnostics or therapies are required. When possible, prevention will almost always lead to a better outcome for the patient. Quality of life is as important a consideration in health care as is longevity. Wisdom is the knowledge that comes from experience in guiding the patient’s care. Optimal health care is a collaboration between the patient and the health care providers. Health care providers and researchers who wish to improve the care of their patients must remain students for life.

Board Certifications

  • Chemical Pathology
    American Board of Pathology
  • Pediatric Endocrinology
    American Board of Pediatrics
  • Pediatrics
    American Board of Pediatrics

Clinical Profile

Dr. Winter holds medical boards in pediatrics (from the American Board of Pediatrics), pediatric endocrinology (from the American Board of Pediatrics) and chemical pathology (from the American Board of Pathology). He also is boarded by the American Board of Clinical Chemistry (ABCC). Dr. Winter is a fellow of the College of American Pathologists (FCAP) and a fellow of the Association for Diagnostics and Laboratory Medicine (FADLM). Dr. Winter was a staff clinical chemist for UFH Shands Hospital. His responsibilities included serum, urine and hemoglobin electrophoresis as well as immunofixation electrophoresis and immunotyping. At the time of his retirement, Dr. Winter was the medical director for the Clinical Laboratory Support Services (CLSC, phlebotomy) and Point of Care Testing (POCT).

Specialties
  • Pathology, Immunology and Laboratory Medicine
Subspecialties
  • Chemical Pathology
  • Clinical Pathology
  • Pediatric Endocrinology
Areas of Interest
  • Diabetes
  • Type 1 diabetes
  • Type 2 diabetes

Research Profile

As an NIH-funded independent investigator since 2000, at the time of his retirement, he was Principle Investigator for the Type 1 Diabetes TrialNet Islet Cell Autoantibody Core Laboratory, The Environmental Determinants of Diabetes in the Young (TEDDY) Core Laboratory (including the Islet Autoantibody Standardization Program), and the Rare and Atypical Diabetes Network (RADIANT) Central Laboratory.

Open Researcher and Contributor ID (ORCID)

0000-0002-7704-0081

Areas of Interest
  • Cardiovascular Disease
  • Diabetes
  • Laboratory Medicine
  • Metabolic syndrome
  • Pediatric Endocrinology

Publications

2024
Diabetes Study of Children of Diverse Ethnicity and Race: Study design.
Diabetes/metabolism research and reviews. 40(3) [DOI] 10.1002/dmrr.3744. [PMID] 37888801.
2024
High Prevalence of A−β+ Ketosis-Prone Diabetes in Children with Type 2 Diabetes and Diabetic Ketoacidosis at Diagnosis: Evidence from the Rare and Atypical Diabetes Network (RADIANT)
Pediatric Diabetes. 2024:1-10 [DOI] 10.1155/2024/5907924.
2023
2022 AACC Preanalytical Phase Conference Abstracts.
The journal of applied laboratory medicine. 8(3):655-659 [DOI] 10.1093/jalm/jfad015. [PMID] 36970886.
2023
Dysfibrinogenemia: discrepant results following infusion of purified fibrinogen.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis. 34(5):337-344 [DOI] 10.1097/MBC.0000000000001237. [PMID] 37395199.
2023
Hematology and coagulation preanalytics for clinical chemists: Factors intrinsic to the sample and extrinsic to the patient.
Clinical biochemistry. 115:3-12 [DOI] 10.1016/j.clinbiochem.2022.11.012. [PMID] 36493884.
2023
Iron Biology – An Overview for Laboratorians.
Annals of clinical and laboratory science. 53(5):681-695 [PMID] 37945025.
2023
Islet Autoantibody Standardization Program: interlaboratory comparison of insulin autoantibody assay performance in 2018 and 2020 workshops.
Diabetologia. 66(5):897-912 [DOI] 10.1007/s00125-023-05877-9. [PMID] 36759347.
2023
What Is the True HbA1c? A HbA1C Peak in the Absence of HbA in an Adult Patient without Sickle Cell Disease.
The journal of applied laboratory medicine. 8(2):425-428 [DOI] 10.1093/jalm/jfac125. [PMID] 36495140.
2022
A Rational Approach to Coagulation Testing.
Laboratory medicine. 53(4):349-359 [DOI] 10.1093/labmed/lmac005. [PMID] 35285898.
2022
Practical Clinical Applications of Islet Autoantibody Testing in Type 1 Diabetes.
The journal of applied laboratory medicine. 7(1):197-205 [DOI] 10.1093/jalm/jfab113. [PMID] 34996067.
2022
Rising to the Challenge: Shortages in Laboratory Medicine.
Clinical chemistry. 68(12):1486-1492 [DOI] 10.1093/clinchem/hvac179. [PMID] 36301321.
2022
Sweet Sphere of Influence.
Clinical chemistry. 68(5):736-737 [DOI] 10.1093/clinchem/hvab224. [PMID] 36103326.
2022
Von Willebrand factor and disease: a review for laboratory professionals.
Critical reviews in clinical laboratory sciences. 59(4):241-256 [DOI] 10.1080/10408363.2021.2014781. [PMID] 34962443.
2021
The Interaction between Hb A1C and Selected Genetic Factors in the African American Population in the USA.
The journal of applied laboratory medicine. 6(1):167-179 [DOI] 10.1093/jalm/jfaa202. [PMID] 33367812.
2021
When Hemoglobin Reported to Be A, S, and F Are Neither A, S, Nor F: A Tale of Two Patients.
The journal of applied laboratory medicine. 6(2):543-549 [DOI] 10.1093/jalm/jfaa087. [PMID] 32995874.
2020
Clotting factors: Clinical biochemistry and their roles as plasma enzymes.
Advances in clinical chemistry. 94:31-84 [DOI] 10.1016/bs.acc.2019.07.008. [PMID] 31952574.
2019
Interference of Hemoglobin A1c Due to Hemoglobin Franklin Park.
The journal of applied laboratory medicine. 3(5):911-913 [DOI] 10.1373/jalm.2018.026781. [PMID] 31639767.
2019
Islet Autoantibody Standardization Program 2018 Workshop: Interlaboratory Comparison of Glutamic Acid Decarboxylase Autoantibody Assay Performance.
Clinical chemistry. 65(9):1141-1152 [DOI] 10.1373/clinchem.2019.304196. [PMID] 31409598.
2018
What Are the Goals of Lipid Testing?
The journal of applied laboratory medicine. 2(5):816-818 [DOI] 10.1373/jalm.2016.022939. [PMID] 33636878.
2017
Coagulation Testing in the Core Laboratory.
Laboratory medicine. 48(4):295-313 [DOI] 10.1093/labmed/lmx050. [PMID] 29126301.
2017
Hyperuricemia and Cardiovascular Disease: What is Left to Prove?
Metabolic syndrome and related disorders. 15(1):1-2 [DOI] 10.1089/met.2016.29010.win. [PMID] 27824511.
2017
Insulin, insulin antibodies and insulin autoantibodies.
MLO: medical laboratory observer. 49(2):16-18 [PMID] 30005474.
2016
Diabetes Technology-Continuous Subcutaneous Insulin Infusion Therapy and Continuous Glucose Monitoring in Adults: An Endocrine Society Clinical Practice Guideline.
The Journal of clinical endocrinology and metabolism. 101(11):3922-3937 [PMID] 27588440.
2016
How Should Total Testosterone Be Measured in Women?
The journal of applied laboratory medicine. 1(2):107-108 [DOI] 10.1373/jalm.2016.020842. [PMID] 33626785.
2015
Commentary.
Clinical chemistry. 61(3) [DOI] 10.1373/clinchem.2014.226951. [PMID] 25725049.
2015
Detection of Antibodies Directed to the N-Terminal Region of GAD Is Dependent on Assay Format and Contributes to Differences in the Specificity of GAD Autoantibody Assays for Type 1 Diabetes.
Diabetes. 64(9):3239-46 [DOI] 10.2337/db14-1693. [PMID] 25972570.
2014
Commentary.
Clinical chemistry. 60(7) [DOI] 10.1373/clinchem.2013.217042. [PMID] 24973430.
2014
Commentary.
Clinical chemistry. 60(4) [DOI] 10.1373/clinchem.2013.214270. [PMID] 24682688.
2014
IgG4 antibodies in autoimmune polyglandular disease and IgG4-related endocrinopathies: pathophysiology and clinical characteristics.
Current opinion in pediatrics. 26(4):493-9 [DOI] 10.1097/MOP.0000000000000107. [PMID] 24905103.
2014
The molecular biology of human iron metabolism.
Laboratory medicine. 45(2):92-102 [PMID] 24868988.
2013
Commentary.
Clinical chemistry. 59(12) [DOI] 10.1373/clinchem.2013.209387. [PMID] 24288093.
2013
Intrathyroidal parathyroid carcinoma: report of an unusual case and review of the literature.
Case reports in pathology. 2013 [DOI] 10.1155/2013/198643. [PMID] 23936709.
2013
Novel detection of pancreatic and duodenal homeobox 1 autoantibodies (PAA) in human sera using luciferase immunoprecipitation systems (LIPS) assay.
International journal of clinical and experimental pathology. 6(6):1202-10 [PMID] 23696946.
2013
Serum from minimal change patients in relapse increases CD80 expression in cultured podocytes.
Pediatric nephrology (Berlin, Germany). 28(9):1803-12 [DOI] 10.1007/s00467-013-2498-4. [PMID] 23689904.
2013
The clinical application of islet autoantibody testing for the diagnosis of autoimmune diabetes.
MLO: medical laboratory observer. 45(10) [PMID] 24294692.
2013
Thyrotropin receptor antibody assays: clinical utility.
American journal of clinical pathology. 139(2):140-2 [DOI] 10.1309/AJCPX5VNAUYN8MUB. [PMID] 23355197.
2012
Commentary.
Clinical chemistry. 58(6) [DOI] 10.1373/clinchem.2012.182170. [PMID] 22641650.
2012
Type 1 Diabetes Associated Auto-Antibodies Are Present in 19\% of Alopecia Areata Sera
Journal of Investigative Dermatology. 132
2011
Autoimmune markers in diabetes.
Clinical chemistry. 57(2):168-75 [DOI] 10.1373/clinchem.2010.148205. [PMID] 21127152.
2011
Comparison of two insulin assays for first-phase insulin release in type 1 diabetes prediction and prevention studies.
Clinica chimica acta; international journal of clinical chemistry. 412(23-24):2128-31 [DOI] 10.1016/j.cca.2011.07.019. [PMID] 21843518.
2010
Autoimmunity predominates in a large South African cohort with Addison’s disease of mainly European descent despite long-standing disease and is associated with HLA DQB*0201.
Clinical endocrinology. 73(3):291-8 [DOI] 10.1111/j.1365-2265.2010.03807.x. [PMID] 20455895.
2010
Enhancing the understanding of pre-type 1 diabetes in the general population.
Diabetes care. 33(6):1403-5 [DOI] 10.2337/dc10-0566. [PMID] 20508234.
2009
Commentary.
Clinical chemistry. 55(11):1908-9 [DOI] 10.1373/clinchem.2009.133769. [PMID] 19864514.
2009
Impact of An Annual Hematology/Oncology Fellow Wet Laboratory Program On Fund of Biomedical Knowledge
Blood. 114
2008
Increased toll-like receptor (TLR) 2 and TLR4 expression in monocytes from patients with type 1 diabetes: further evidence of a proinflammatory state.
The Journal of clinical endocrinology and metabolism. 93(2):578-83 [PMID] 18029454.
2007
Executive summary. The National Academy of Clinical Biochemistry Laboratory Medicine Practice Guideline: evidence-based practice for point-of-care testing.
Clinica chimica acta; international journal of clinical chemistry. 379(1-2):14-28; discussion 29 [PMID] 17270169.
2006
Carcinomas of the female genital tract occurring after pelvic irradiation: a report of 15 cases.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 25(3):293-7 [PMID] 16810069.
2005
Analytic bias of thyroid function tests: analysis of a College of American Pathologists fresh frozen serum pool by 3900 clinical laboratories.
Archives of pathology & laboratory medicine. 129(3):310-7 [PMID] 15737023.
2005
Comparison of pooled fresh frozen serum to proficiency testing material in College of American Pathologists surveys: cortisol and immunoglobulin E.
Archives of pathology & laboratory medicine. 129(3):305-9 [PMID] 15737022.
2004
A Rosetta stone for insulin treatment: self-monitoring of blood glucose.
Clinical chemistry. 50(6):985-7 [PMID] 15161718.
2004
Expression of beta-cell autoimmunity does not differ between potential dizygotic twins and siblings of patients with type 1 diabetes.
Journal of autoimmunity. 23(3):275-9 [PMID] 15501398.
2004
Laboratory and clinical aspects of B-type natriuretic peptides.
Archives of pathology & laboratory medicine. 128(6):697-9 [PMID] 15163225.
2004
Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus–a new surrogate measure of non-progression?
Pediatric diabetes. 5(2):72-9 [PMID] 15189492.
2004
The chemical pathology of insulin resistance and the metabolic syndrome.
MLO: medical laboratory observer. 36(10):20, 22-5 [PMID] 15536804.
2004
The role and assessment of ventricular peptides in heart failure.
Clinics in laboratory medicine. 24(1):235-74 [PMID] 15157565.
2003
Newly defined genetic diabetes syndromes: maturity onset diabetes of the young.
Reviews in endocrine & metabolic disorders. 4(1):43-51 [PMID] 12618559.
2003
Prevention strategies for type 1 diabetes mellitus: current status and future directions.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy. 17(1):39-64 [PMID] 12534319.
2003
Screening strategies for the identification of multiple antibody-positive relatives of individuals with type 1 diabetes.
The Journal of clinical endocrinology and metabolism. 88(1):103-8 [PMID] 12519837.
2002
Autoimmune polyglandular syndrome. II: Clinical syndrome and treatment.
Endocrinology and metabolism clinics of North America. 31(2):339-52 [PMID] 12092454.
2002
Type 1 diabetes islet autoantibody markers.
Diabetes technology & therapeutics. 4(6):817-39 [PMID] 12614488.
2001
Hardware and software in diabetes mellitus: performance characteristics of hand-held glucose testing devices and the application of glycemic testing to patients’ daily diabetes management.
Clinical chemistry. 47(1):11-2 [PMID] 11148171.
2001
Methylmalonic acid: a test whose time has come?
Archives of pathology & laboratory medicine. 125(6):824-7 [PMID] 11371242.
2001
Review: molecular thyroidology.
Annals of clinical and laboratory science. 31(3):221-44 [PMID] 11508826.
2000
Immunoglobulin E: importance in parasitic infections and hypersensitivity responses.
Archives of pathology & laboratory medicine. 124(9):1382-5 [PMID] 10975945.
2000
Molecular and genetic bases for maturity onset diabetes of youth.
Current opinion in pediatrics. 12(4):388-93 [PMID] 10943822.
1999
Emerging epidemic of type 2 diabetes in youth.
Diabetes care. 22(2):345-54 [PMID] 10333956.
1999
Monogenic diabetes mellitus in youth. The MODY syndromes.
Endocrinology and metabolism clinics of North America. 28(4):765-85 [PMID] 10609119.
1999
Tacrolimus-based triple-drug immunosuppression minimizes serum lipid elevations in pediatric cardiac transplant recipients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 18(7):707-13 [PMID] 10452348.
1999
The endocrinology of growth failure.
MLO: medical laboratory observer. 31(12):30-5; quiz 36 [PMID] 11184280.
1998
Non-insulin dependent diabetes mellitus (NIDDM) in minority youth: research priorities and needs.
Clinical pediatrics. 37(2):143-52 [PMID] 9492123.
1997
Autoimmune diabetes. The role of autoantibody markers in the prediction and prevention of insulin-dependent diabetes mellitus.
Clinics in laboratory medicine. 17(3):499-545 [PMID] 9316771.
1997
Pharmacological approaches to the prevention of autoimmune diabetes.
Drugs. 53(6):943-56 [PMID] 9179526.
1996
Macrophage-silicone interactions in women with breast prostheses.
Current topics in microbiology and immunology. 210:245-52 [PMID] 8565562.
1996
Type I insulin-dependent diabetes mellitus: a model for autoimmune polygenic disorders.
Advances in dental research. 10(1):81-7 [PMID] 8934932.
1995
Recent advances in the immunopathogenesis of insulin-dependent diabetes mellitus.
Current opinion in pediatrics. 7(4):459-65 [PMID] 7581652.
1994
Islet cell antibodies predict insulin-dependent diabetes in United States school age children as powerfully as in unaffected relatives.
The Journal of clinical investigation. 93(6):2403-7 [PMID] 8200974.
1993
Insulin-dependent diabetes in the NOD mouse model. I. Detection and characterization of autoantibody bound to the surface of pancreatic beta cells prior to development of the insulitis lesion in prediabetic NOD mice.
Autoimmunity. 15(2):123-35 [PMID] 8218837.
1993
Insulin-dependent diabetes in the NOD mouse model. II. Beta cell destruction in autoimmune diabetes is a TH2 and not a TH1 mediated event.
Autoimmunity. 15(2):113-22 [PMID] 8105989.
1993
Pediatric approach to prevention of coronary heart disease.
The Journal of the Florida Medical Association. 80(10):679-83 [PMID] 8270900.
1993
Relationship of T-uptake and thyroxine in hypo- and hyperthyroid patients.
Clinical chemistry. 39(3) [PMID] 8448882.
1993
The genetics of autoimmune diabetes. Approaching a solution to the problem.
American journal of diseases of children (1960). 147(12):1282-90 [PMID] 8249945.
1992
Clinical and molecular aspects of autoimmune endocrine disease.
Concepts in immunopathology. 8:189-221 [PMID] 1735102.
1992
Encainide-induced diabetes: analysis of islet cell function.
Research communications in chemical pathology and pharmacology. 76(3):259-68 [PMID] 1636050.
1992
Kanamycin inhibits cochlear-renal ODC in neonatal rats.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 107(4):501-10 [PMID] 1437181.
1992
T cell receptor beta diversity and joining segments in the NOD mouse.
Autoimmunity. 12(1):9-12 [PMID] 1535516.
1991
Hypercholesterolemia. A common problem in Florida school-age children and adolescents.
Annals of the New York Academy of Sciences. 623:472-5 [PMID] 2042874.
1990
Flow cytometric enumeration of mononuclear cell populations infiltrating the islets of Langerhans in prediabetic NOD mice: development of a model of autoimmune insulitis for type I diabetes.
Regional immunology. 3(6):305-17 [PMID] 2132756.
1990
Immunogenetic analysis of beta-cell autoimmunity in NOD mice. Relationship of insulitis to T-lymphocyte-receptor beta nod and A beta nod genes.
Diabetes. 39(8):975-82 [PMID] 1973674.
1989
Natural history of incidental hyperglycemia and glycosuria of childhood.
The Journal of pediatrics. 115(5 Pt 1):676-80 [PMID] 2681635.
1988
Dietary protein restriction reduces the frequency and delays the onset of insulin dependent diabetes in BB rats.
Autoimmunity. 2(1):11-9 [PMID] 3155150.
1988
Familial diabetes mellitus.
Diabetologia. 31(2):127-8 [PMID] 3360223.
1988
Identification of insulin-dependent diabetes mellitus before the onset of clinical symptoms.
The Journal of pediatrics. 112(2):314-6 [PMID] 3276866.
1988
Thymosin and the spontaneously diabetic BB rat.
Autoimmunity. 1(2):115-23 [PMID] 2979610.
1987
Bovine albumin antibodies in NOD mice.
Diabetes research (Edinburgh, Scotland). 6(2):67-9 [PMID] 3427869.
1987
Immunosuppressive therapy in insulin dependent diabetes.
Acta paediatrica Japonica : Overseas edition. 29(3):349-54 [PMID] 3144862.
1987
Is insulin-dependent diabetes mellitus a preventable disease?
Clinical and investigative medicine. Medecine clinique et experimentale. 10(5):444-9 [PMID] 3315366.
1987
Maturity-onset diabetes of youth in black Americans.
The New England journal of medicine. 316(6):285-91 [PMID] 3543673.
1987
Restriction-fragment-length polymorphisms of 5′-flanking region of insulin I gene in BB and other rat strains. Absence of association with IDDM.
Diabetes. 36(2):193-8 [PMID] 2879755.
1986
Are insulin autoantibodies markers for insulin-dependent diabetes mellitus?
Diabetes. 35(8):894-8 [PMID] 3525287.
1986
Congenital pancreatic hypoplasia: a syndrome of exocrine and endocrine pancreatic insufficiency.
The Journal of pediatrics. 109(3):465-8 [PMID] 3746536.
1986
Molecular genetics of insulin-dependent diabetes mellitus.
Molecular biology & medicine. 3(2):129-36 [PMID] 3526080.
1985
Type I insulin dependent diabetes: an autoimmune disease that can be arrested or prevented with immunotherapy?
Advances in pediatrics. 32:159-75 [PMID] 3909773.
1984
Familial DiGeorge syndrome with tetralogy of Fallot and prolonged survival.
European journal of pediatrics. 141(3):171-2 [PMID] 6698063.
1984
Pancreatic alpha cell autoantibodies and glucagon response to arginine.
Diabetes. 33(5):435-7 [PMID] 6373451.
1983
Autosomal dominant hypoparathyroidism with variable, age-dependent severity.
The Journal of pediatrics. 103(3):387-90 [PMID] 6886902.
1983
Neural crest cell migration to placenta.
American journal of clinical pathology. 79(1):141-2 [PMID] 6849291.
1982
Solitary central maxillary incisor associated with precocious puberty and hypothalamic hamartoma.
The Journal of pediatrics. 101(6):965-7 [PMID] 7143176.

Grants

Apr 2023 ACTIVE
Limited Competition: Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in the Young Study (TEDDY)
Role: Co-Project Director/Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Nov 2020 – Oct 2023
A Multiple Ascending Dose Trial Investigating Safety, Tolerability And Pharmacokinetics Of NNC0361-0041 Administered Subcutaneously To Patients With TID (TN-27)
Role: Project Manager
Funding: UNIV OF SOUTH FLORIDA via NOVO NORDISK
Nov 2020 – Nov 2020
A Multiple Ascending Dose Trial Investigating Safety, Tolerability And Pharmacokinetics Of NNC0361-0041 Administered Subcutaneously To Patients With TID (TN-27)
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Aug 2020 – Mar 2023
The Environmental Determinants of Diabetes in the Young (TEDDY) Study
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Jun 2020 ACTIVE
RADIANT Core Laboratory Proposal 2020-21
Role: Project Manager
Funding: UNIV OF CHICAGO via NATL INST OF HLTH NIDDK
Jan 2020 ACTIVE
Data Coordinating Center for Type 1 Diabetes TrialNet
Role: Project Manager
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Aug 2019 – Jul 2020
The Environmental Determinants of Diabetes in the Young (TEDDY) Study
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Aug 2018 – Jul 2019
The Environmental Determinants of Diabetes in the Young (TEDDY) Study
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Mar 2018 – Dec 2019
NIDDK Type 1 Diabetes TrialNet Data Coordinating Center
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Jan 2018 – Apr 2020
The Enviromental Determinants of Diabetes in the Young (TEDDY) Study
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Mar 2017 – Feb 2018
2017-2018 TrialNet
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Sep 2016 – Feb 2017
TrialNet ICA DPT-1 Laboratory (Diabetes Prevention)
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Jun 2016 – Dec 2017
ISLET AUTOANTIBODY STANDARDIZATION PROGRAM (IASP)
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Jun 2016 – May 2017
Anti-thymocyte Globulin (Rabbit) (Thymoglobulin?) and Pegylated GCSF (Neulasta?) in New Type 1 Diabetes Protocol TN-19
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via SANOFI US SERVICES
Mar 2016 – Dec 2021
Highly Sensitive and Specific MSD Multiplexed Autoimmune Disease Panel
Role: Principal Investigator
Funding: MESO SCALE DIAGNOSTICS via NATL INST OF HLTH NIAID
Nov 2014 – May 2016
Anti-thymocyte Globulin (rabbit)(thymoglobulin)
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via SANOFI US SERVICES
Mar 2014 – May 2016
Islet Autoantibody Standardization Program (IASP)
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via NATL INST OF HLTH NIDDK
Oct 2013 – Sep 2016
Safety and Efficacy of Imatinib for Preserving Beta-cell Function in New-onset Type 1 Diabetes Mellitus
Role: Principal Investigator
Funding: UNIV OF SOUTH FLORIDA via JDRF

Education

Fellowship – Pediatric Endocrinology
1984 · University of Florida
Residency – Pediatrics
1981 · University of Kentucky, Lexington, Ky
Internship – Pediatrics
1978 · University of Kentucky, Lexington, Ky
Medical Degree
1977 · Loyola Stritch School of Medicine

Contact Details

Phones:
Business:
(352) 294-5540
Emails:
Business:
wwinter@ufl.edu
Addresses:
Business Mailing:
PO Box 100275 RM
1600 SW ARCHER RD D6 3
GAINESVILLE FL 32610
Business Street:
D6-3, DENTAL SCIENCES BUILDING
GAINESVILLE FL 326100275