Alpha-Fetoprotein (AFP), Maternal Serum for Open Spina Bifida
Note: No isotopes should be administered to the patient within 24 hours prior to the venipuncture.
Container/Tube: Gel-barrier tube, no thrombin additive
Collection: Separate serum from cells. Avoid hemolysis. Send the complete specimen in its original tube. Do not pour-off.
Sample Volume: 3 mL
Minimum Volume: 0.4 mL (Repeat testing is not possible with this specimen volume.)
Storage: Store specimens at room temperature.
- Ambient: 7 days
- Refrigerated: 14 days
- Frozen: 14 days
- Freeze/Thaw cycles: Stable (x3)
- Gross hemolysis
- Gross lipemia
- Quantity not sufficient (QNS)
UFHPL Test #: 28010
This test screens for open spina bifida. This test does not screen for Down syndrome or trisomy 18. The following information must be provided: gestational age, date on which the patient was the stated gestation age, how gestational age was determined (LMP, EDD, US), patient's weight, patient's date of birth, patient's race (white, black, other), and insulin-dependent diabetic status. Also indicate relevant patient history, such as prior neural tube defects, ultrasound anomalies, or previous maternal serum screening during this pregnancy. Complete information is necessary to interpret the test. Patient information may be provided to the laboratory using the Maternal Prenatal Screening request form (0900). Specimens must be collected before amniocentesis.