Amniotic Fluid: Chromosome Study

Methodology: 
Classic cytogenetic G-band analysis (karyotyping); requires cell culture*
Performed: 
Monday - Saturday
Reported: 
10 - 14 days
Use: 

This test is used to detect fetal chromosome abnormalities.

Result: 
Interpretive report
Specimen Requirements: 

Amniotic Fluid: Aseptically collect approximately 1 cc of amniotic fluid of per week of gestational age in two sterile 15 mL conical centrifuge tubes and sequentially label the tubes. The initial 1 - 2 cc should not be included for chromosome studies (but may be utilized for AFP testing).

Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 - 48 hours. Ship specimens at room temperature for overnight delivery.

Unacceptable Conditions:
  • Frozen specimens
  • Specimens greater than 48 hours old*
Stability (collection to initiation of testing):
  • Ambient: 24 - 48 hours*
  • Frozen: Unacceptable

* Cell viability of specimens requiring cell culture may be compromised in specimens more than 48 hours old upon receipt. Refrigeration at 2° - 8° C may assist when a delay is not preventable. Do not freeze or place specimens directly on ice.

CPT Code (s): 

88235, 88269, 88285, 88280, 88291

Notes: 

Adjustments and/or additional CPT codes and/or modifiers may be warranted

UFHPL Test #: 30020

Test Directory