Chromosome Study: Chorionic Villi

Methodology: 
Classic cytogenetic G-band analysis (karyotyping); requires cell culture
Performed: 
Monday - Saturday
Reported: 
10 - 14 days
Use: 

This test is used to detect fetal chromosome abnormalities at 11 - 15 weeks of gestation.

Result: 
By report; interpretive
Specimen Requirements: 

Chorionic Villi: Collect 10 - 30 mg of chorionic villi, utilizing aspiration medium, containing sodium heparin. After assessment of the appropriate amount and quality of villi, transfer it to a sterile centrifuge tube with a transportation medium.

Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 - 48 hours. Ship specimens at room temperature for overnight delivery.

  • Unacceptable Conditions:
    • Frozen specimens
    • Specimens greater than 48 hours old*
  • Stability (collection to initiation of testing):
    • Ambient: 24 - 48 hours old*
    • Frozen: Unacceptable

* Cell viability of specimens requiring cell culture may be compromised in specimens more than 48 hours old upon receipt. Refrigeration at 2° - 8° C may assist when a delay in delivery is unpreventable. Do not freeze or place specimens directly on ice.

Reference Values: 

By report; interpretive

CPT Code (s): 
  • 88235
  • 88267
  • 88285
  • 88280
  • 88291
Notes: 

UFHPL Test #: 30030

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