Gestational Trophoblast Disease Evaluation (Partial vs. Complete Mole) [p57 Immunohistochemistry (IHC), DNA Ploidy by Flow Cytometry]

Additional Information:


UFHPL Test #: 90030

CPT Code(s):

  • 88182
  • 88342

Collection Procedure:


Specimen Requirements:

Paraffin block

Storage/Transport: Ship specimens at 20° – 25° C to protect them from excessive heat. Include a surgical pathology report.

Unacceptable Specimens:
  • Specimens that do not contain placental villi with trophoblast
  • Specimens in fixatives other than 10% formalin
  • Specimens in Bouin, B5, Omni or Carnoy’s Solution
Stability (collection to initiation of testing):
  • Ambient: Formalin-fixed paraffin block

Antibody: p57Kip2

Detection Method: EnVision + Dual Link System HRP

Use:

This test is used to evaluate gestational trophoblastic diseases, including partial and complete molar pregnancy.

Methodology:


Flow cytometry and IHC staining with p57

Reported:


7 days

Reference Values:


Interpretation Data: