Insulin Autoantibodies (IAA)
- Diagnosis of Type 1 Diabetes: The presence of autoantibodies against insulin (IAA) in patients with diabetes mellitus indicates the presence of autoimmune, type 1 diabetes. It is advised that blood for IAA testing be drawn before insulin therapy is initiated. For the IAA result to be valid, the patient must not be insulin treated for more than 1 week.
- Prediction of Type 1 Diabetes: Autoantibodies against insulin in an asymptomatic individual places the subject at increased risk for the development of type 1 diabetes.
Collect blood in a 1- 5 mL serum separator tube. Centrifuge, separate and transfer the serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.
- Ambient: 24 hours
- Refrigerated: 24 hours
- Frozen: 1 year (Avoid repeated freeze/thaw cycles.)
Negative: < 95 nU/mL
Indeterminate: 95 - 124 nU/mL
- Positive: > 125 nU/mL