Insulinoma Associated-2 Autoantibodies (IA-2A)

Additional Information:

EPIC Test Name: IA2 AUTOANTIBODIES

CPT Code(s):

86341

Specimen Requirements:

Type: Serum
Container/Tube: SST
Sample Volume: 1 mL
Minimum Volume: 0.1 mL (Repeat testing is not possible with this specimen volume.)
Storage: Centrifuge, separate and transfer the serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.
Stability (collection to time of analysis/testing):

  • Refrigerated: 24 hours
  • Frozen: 1 year

Use:

  • Diagnosis of Type 1 Diabetes: The presence of autoantibodies against IA-2 (IA-2A) in patients with diabetes mellitus indicates the presence of autoimmune, type 1 diabetes.
  • Prediction of Type 1 Diabetes: Autoantibodies against IA-2 (IA-2A) in an asymptomatic individual places the subject at increased risk for the development of type 1 diabetes.

Methodology:

Radioimmunoassay

Reported:

2 - 10 business days

Reference Values:

Negative: < 0.90 U/mL
Positive: ≥ 0.90 U/mL

Performed:

Bi-weekly