Chromosome Study: Neoplastic Solid Tumor

CPT Code(s):

  • 88239
  • 88262
  • 88291


Classic cytogenetic G-band analysis (karyotyping); requires cell culture


Monday - Saturday


7 - 21 days


This test is used to detect clonal cytogenetic changes in solid tumor tissue specimens which may provide classification and prognostic information.

Specimen Requirements:

Solid Tumor Tissue: Aseptically obtain a sample (approximately 2 mm x 2 mm x 2 mm) and deposit it in RPMI or tissue culture medium.*

Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 - 48 hours. Ship specimens at room temperature for overnight delivery.

Unacceptable Conditions:

  • Frozen specimens
  • Formalin, alcohol, or paraffin-preserved specimens
Stability (collection to initiation of testing):

  • Ambient: 24 - 48 hours old*
  • Frozen: Unacceptable

* Cell viability of specimens requiring cell culture may be compromised in specimens greater than 48 hours old upon receipt. Refrigeration at 2° - 8° C may assist when a delay in delivery is unpreventable. Do not freeze or place specimens directly on ice.

Collection Procedure:


Reference Values:

By report; interpretive

Interpretation Data:



UFHPL Test #: 30045

Reported Notes: