Thyroglobulin Autoantibodies (TGA)

Additional Information:

EPIC Test Name: THYROGLOBULIN ANTIBODY

CPT Code(s):

86800

Collection Procedure:

Collect specimen in SST tube. Allow to clot. Centrifuge and store refrigerated . Transport to lab.

Specimen Requirements:

Specimen Type: Serum
Container/Tube: SST
Sample Volume: 1 mL
Minimum Volume: 0.1 mL (Repeat testing is not possible with this specimen volume.)
Storage: Refrigerate
Stability (collection to time of analysis/testing):

  • Refrigerated: 7 days
  • Frozen: Indefinitely

Use:

  • Diagnosis of Autoimmune Thyroid Disease: The detection of either thyroperoxidase autoantibodies (TPOA) or thyroglobulin autoantibodies (TGA) in the presence of biochemically defined hypothyroidism or euthyroid goiter identifies an autoimmune etiology as the cause of the subject’s thyroid disease.
  • Prediction of Autoimmune Thyroid Disease: The detection of TPOA and/or TGA in an asymptomatic individual indicates an increased risk for the subsequent development of auto immune thyroid disease that can produce goiter and/or either hypothyroidism (Hashimoto thyroid or atropic thyroiditis) or hyperthyroidism (Graves’ disease).

Methodology:

Radioimmunoassay

Reported:

1-10 business days

Reference Values:

<1.0 U/mL

Performed:

Weekly