Zinc Transporter 8 Autoantibody (ZnT8A)

Enzyme-linked immunosorbent assay (ELISA)
1 - 3 days
Reported Notes: 
Turnaround Time: 3 - 13 days
  • Diagnosis of Type 1 Diabetes: Zinc transporter 8 autoantibodies (ZnT8A) in patients with diabetes mellitus indicate that the etiology of the diabetes is autoimmune (i.e., type 1 diabetes). ZnT8A are also valuable in the diagnosis of latent autoimmune diabetes of adulthood (LADA).
  • Prediction of Type 1 Diabetes: ZnT8A in an asymptomatic individual places the subject at increased risk for developing type 1 diabetes.
  • Relationship of ZnT8A to Beta-Cell Function, Following Pancreas Transplantation: The presence of ZnT8A in the serum of patients who have undergone a pancreas transplant predicts beta-cell failure.
Specimen Requirements: 

Collect blood in a 1- 5 mL serum separator tube. Centrifuge, separate and transfer the serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.

Stability (collection to shipping of the sample):
  • Ambient: 24 hours
  • Refrigerated: 24 hours
  • Frozen: 1 year (Avoid repeated freeze/thaw cycles.)
Reference Values: 
  • Negative: < 15 U/mL
  • Positive: > 15
CPT Code (s): 

UFHPL Test #: 60155

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