Kristianna M Fredenburg

Kristianna M Fredenburg, MD, PhD

Ast Prof

Department: MD-PATHOLOGY-GENERAL

About Kristianna M Fredenburg

Kristianna Fredenburg, M.D., Ph.D., joined the University of Florida Department of Pathology, Immunology, and Laboratory Medicine in July 2015. She is a board-certified anatomic and clinical pathologist whose primary interests include head/neck and cardiothoracic pathology. She also has a strong research interest in identifying the underlying pathogenesis of head and neck cancers among different racial and ethnic groups in the United States.  

Dr. Fredenburg earned her undergraduate degree in biology from the University of Rochester in Rochester, New York. She followed this degree with a doctorate in cell biology from North Carolina State University in Raleigh, North Carolina. After a postdoctoral fellowship at the Duke University Department of Molecular Genetics and Microbiology (Durham, North Carolina), Dr. Fredenburg went on to obtain her medical degree from the University of North Carolina at Chapel Hill. She later completed her pathology residency training and a two-year surgical pathology fellowship here, at the University of Florida.

Teaching Profile

Courses Taught
2017-2018,2020-2024
DEN6350 General Pathology

Board Certifications

  • Anatomic & Clinical Pathology
    American Board of Pathology

Clinical Profile

Subspecialties
  • Anatomic and Clinical Pathology

Publications

2023
Association of Suppressive Myeloid Cell Enrichment with Aggressive Oropharynx Squamous Cell Carcinoma.
Cancers. 15(8) [DOI] 10.3390/cancers15082346. [PMID] 37190274.
2023
Characterization of GATA3 and Mammaglobin in breast tumors from African American Women.
Archives of microbiology & immunology. 7(1):18-28 [DOI] 10.26502/ami.936500101. [PMID] 37383682.
2023
Florida-California Cancer Research, Education and Engagement (CaRE2) Health Equity Center: Structure, Innovations, and Initial Outcomes.
Cancer control : journal of the Moffitt Cancer Center. 30 [DOI] 10.1177/10732748231197878. [PMID] 37703814.
2023
Identifying locally actionable strategies to increase participant acceptability and feasibility to participate in Phase I cancer clinical trials.
Health expectations : an international journal of public participation in health care and health policy. 27(1) [DOI] 10.1111/hex.13920. [PMID] 38041447.
2023
Investigating miR-9 as a mediator in laryngeal cancer health disparities.
Frontiers in oncology. 13 [DOI] 10.3389/fonc.2023.1096882. [PMID] 37081981.
2023
Lung microhaemorrhage drives oxidative/inflammatory damage in α1-antitrypsin deficiency.
ERJ open research. 9(3) [DOI] 10.1183/23120541.00662-2022. [PMID] 37313399.
2023
Opportunities and Challenges of Kava in Lung Cancer Prevention.
International journal of molecular sciences. 24(11) [DOI] 10.3390/ijms24119539. [PMID] 37298489.
2023
The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 32(4):516-523 [DOI] 10.1158/1055-9965.EPI-22-1167. [PMID] 36780193.
2023
Thoracoliths in Pleural Space Mimicking Lung Cancer: A Case Report.
Cureus. 15(11) [DOI] 10.7759/cureus.48522. [PMID] 38073921.
2022
A 40-Year-Old Woman With COVID-19 and Bilateral Vision Loss.
The Neurohospitalist. 12(4):664-668 [DOI] 10.1177/19418744221114209. [PMID] 36147755.
2022
Cell Dissociation Enzymes Affect Annexin V/Flow-Cytometric Apoptotic Assay Outcomes After miRNA-based Transient Transfection.
Anticancer research. 42(6):2819-2825 [DOI] 10.21873/anticanres.15763. [PMID] 35641293.
2022
TLR7 Activation Accelerates Cardiovascular Pathology in a Mouse Model of Lupus.
Frontiers in immunology. 13 [DOI] 10.3389/fimmu.2022.914468. [PMID] 35860280.
2021
Lower disease control rates and survival outcomes among Blacks with pharyngeal squamous cell carcinomas compared with Whites: a retrospective analysis at the University of Florida.
Cancer causes & control : CCC. 32(11):1269-1278 [DOI] 10.1007/s10552-021-01477-3. [PMID] 34259972.
2020
[Not Available].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 18(3):253-255 [DOI] 10.1111/ddg.14043_g. [PMID] 32130776.
2020
Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury.
Cell death & disease. 11(2) [DOI] 10.1038/s41419-020-2269-7. [PMID] 32080178.
2020
Merkel cell carcinoma of an unknown primary.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 18(3):253-255 [DOI] 10.1111/ddg.14043. [PMID] 32077591.
2020
T cells expressing the lupus susceptibility allele Pbx1d enhance autoimmunity and atherosclerosis in dyslipidemic mice.
JCI insight. 5(11) [DOI] 10.1172/jci.insight.138274. [PMID] 32493841.
2019
Chronic opioid use in patients undergoing treatment for oropharyngeal cancer.
The Laryngoscope. 129(9):2087-2093 [DOI] 10.1002/lary.27791. [PMID] 30613983.
2019
Knockout of Acinar Enriched microRNAs in Mice Promote Duct Formation But Not Pancreatic Cancer.
Scientific reports. 9(1) [DOI] 10.1038/s41598-019-47566-x. [PMID] 31367007.
2019
MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma.
Oral oncology. 98:147-155 [DOI] 10.1016/j.oraloncology.2019.09.005. [PMID] 31606723.
2019
Smoking-related diffuse cystic lung disease.
Respiratory medicine case reports. 28 [DOI] 10.1016/j.rmcr.2019.100912. [PMID] 31384548.
2018
CD70 as a target for chimeric antigen receptor T cells in head and neck squamous cell carcinoma.
Oral oncology. 78:145-150 [DOI] 10.1016/j.oraloncology.2018.01.024. [PMID] 29496042.
2018
Eps8 expression is significantly lower in p16+ head and neck squamous cell carcinomas (HNSCCs) compared with p16- HNSCCs.
Human pathology. 72:45-51 [DOI] 10.1016/j.humpath.2017.10.021. [PMID] 29107665.
2018
Personalized Tumor RNA Loaded Lipid-Nanoparticles Prime the Systemic and Intratumoral Milieu for Response to Cancer Immunotherapy.
Nano letters. 18(10):6195-6206 [DOI] 10.1021/acs.nanolett.8b02179. [PMID] 30259750.
2018
Primary orbital melanoma treated with orbital exenteration and postoperative radiotherapy: A case report and review of the literature.
Head & neck. 40(3):E17-E20 [DOI] 10.1002/hed.24983. [PMID] 29394463.
2017
Slow-Growing Infiltrative Sinonasal Mass.
JAMA otolaryngology– head & neck surgery. 143(6):625-626 [DOI] 10.1001/jamaoto.2016.3693. [PMID] 28253397.
2016
Base of tongue squamous cell carcinoma with infiltrative bone marrow carcinomatosis after definitive chemoradiation: A case report.
Head & neck. 38(7):E2449-E2453 [DOI] 10.1002/hed.24155. [PMID] 26040510.
2015
Cervical cancer with a rare umbilical metastases in prior surgical site.
International journal of surgery case reports. 17:8-11 [DOI] 10.1016/j.ijscr.2015.10.016. [PMID] 26519808.
2015
Our Journey from the Study of Human Autoantibodies to the microRNA World.
Frontiers in immunology. 6 [DOI] 10.3389/fimmu.2015.00110. [PMID] 25814992.
2015
Severity of influenza A(H1N1) illness and emergence of D225G variant, 2013-14 influenza season, Florida, USA.
Emerging infectious diseases. 21(4):664-7 [DOI] 10.3201/eid2104.141375. [PMID] 25811540.

Grants

Sep 2023 ACTIVE
2/3 Florida-California Cancer Research, Education & Engagement (CaRE2) Health Equity Center
Role: Other
Funding: NATL INST OF HLTH NCI
Apr 2023 ACTIVE
AB-free kava in lung cancer chemoprevention
Role: Co-Investigator
Funding: FL DEPT OF HLTH BANKHEAD-COLEY CANCER RE
Aug 2022 ACTIVE
Investigating miR-9-5p and its targets as interventional and clinicopathologic predictors of laryngeal cancer racial disparate outcomes
Role: Principal Investigator
Funding: US ARMY MED RES ACQUISITION
Sep 2018 – Aug 2023
2/3 Florida-California Cancer Research, Education & Engagement (CaRE2) Health Equity Center
Role: Other
Funding: NATL INST OF HLTH NCI
Apr 2017 – Jun 2021
OoR CTSI Institutional Matching Support
Role: Project Manager
Funding: UF DIV OF SPONSORED RES MATCHING FUNDS
Feb 2015 – Oct 2023
UF Health Cancer Center Pilot Project Grants funded through the Florida Consortium of National Cancer Institute Centers Program
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL

Education

Fellowship – Pathology
2015 · University of Florida
Residency – Clinical & Anatomic Pathology
2013 · University of Florida
Medical Degree
2008 · University of North Carolina

Contact Details

Emails:
Addresses:
Business Mailing:
PO BOX 100275
DEPT OF PATHOLOLGY, UNIVERSITY OF FLORIDA
GAINESVILLE FL 326100275
Business Street:
1600 SW ARCHER RD
GAINESVILLE FL 32610