Lijun Yang,
PROFESSOR
Teaching Profile
Courses Taught
2011-2018,2020-2022
DEN6350 General Pathology
2018
GMS7979 Advanced Research
Board Certifications
-
Lijun YangHematopathology
-
Lijun YangClinical Pathology
-
Lijun YangAnatomic Pathology
Clinical Profile
Specialties
- Pathology, Immunology and Laboratory Medicine
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-0522-3292
Publications
2021
Classical Hodgkin Lymphoma Presenting as a Sigmoid Mass.
Gastroenterology research.
14(3):204-208
[DOI] 10.14740/gr1409.
[PMID] 34267838.
2021
Reply.
Arthritis & rheumatology (Hoboken, N.J.).
73(1):176-178
[DOI] 10.1002/art.41478.
[PMID] 32776428.
2020
Differential Responsiveness of Monocyte and Macrophage Subsets to Interferon.
Arthritis & rheumatology (Hoboken, N.J.).
72(1):100-113
[DOI] 10.1002/art.41072.
[PMID] 31390156.
2020
NF-E2-Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus.
Arthritis & rheumatology (Hoboken, N.J.).
72(10):1707-1720
[DOI] 10.1002/art.41383.
[PMID] 32500632.
2018
Primary Gastric EBV-positive Diffuse Large B Cell Lymphoma (DLBCL) of the Elderly with Plasmablastic Differentiation.
In vivo (Athens, Greece).
32(2):413-417
[PMID] 29475930.
2017
Uncovering stem cell differentiation factors for salivary gland regeneration by quantitative analysis of differential proteomes.
PloS one.
12(2)
[DOI] 10.1371/journal.pone.0169677.
[PMID] 28158262.
2016
Cell-Permeable Peptide Blocks Tlr4 Signaling and Improves Islet Allograft Survival
Cell Transplantation.
25(7):1319-1329
[DOI] 10.3727/096368916X690449.
2016
Irisin Inhibits Atherosclerosis by Promoting Endothelial Proliferation Through microRNA126-5p.
Journal of the American Heart Association.
5(9)
[PMID] 27671318.
2016
Protective Effect of Irisin on Atherosclerosis via Suppressing Oxidized Low Density Lipoprotein Induced Vascular Inflammation and Endothelial Dysfunction.
PloS one.
11(6)
[DOI] 10.1371/journal.pone.0158038.
[PMID] 27355581.
2015
Animal Models of Interferon Signature Positive Lupus.
Frontiers in immunology.
6
[DOI] 10.3389/fimmu.2015.00291.
[PMID] 26097482.
2015
Irisin Induces Angiogenesis in Human Umbilical Vein Endothelial Cells In Vitro and in Zebrafish Embryos In Vivo via Activation of the ERK Signaling Pathway.
PloS one.
10(8)
[DOI] 10.1371/journal.pone.0134662.
[PMID] 26241478.
2015
Mechanisms of autoantibody production in systemic lupus erythematosus.
Frontiers in immunology.
6
[DOI] 10.3389/fimmu.2015.00228.
[PMID] 26029213.
2015
Mechanisms of tumor necrosis factor α antagonist-induced lupus in a murine model.
Arthritis & rheumatology (Hoboken, N.J.).
67(1):225-37
[DOI] 10.1002/art.38882.
[PMID] 25252121.
2015
STAT3 signaling contributes to the high effector activities of interleukin-15-derived dendritic cells.
Immunology and cell biology.
93(5):461-71
[DOI] 10.1038/icb.2014.103.
[PMID] 25582338.
2014
Bacterial delivery of TALEN proteins for human genome editing.
PloS one.
9(3)
[DOI] 10.1371/journal.pone.0091547.
[PMID] 24618838.
2014
High level expression, efficient purification, and bioactivity of recombinant human metallothionein 3 (rhMT3) from methylotrophic yeast Pichia pastoris.
Protein expression and purification.
101:121-6
[DOI] 10.1016/j.pep.2014.06.009.
[PMID] 24973778.
2014
Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling.
Diabetes.
63(2):514-25
[DOI] 10.2337/db13-1106.
[PMID] 24150604.
2014
Phenotypic Consequences of Tlr7-Driven Interferon and Proinflammatory Cytokine Production in Lupus
Arthritis Research & Therapy.
16(1)
2013
Breast Implant-Associated Alk-Negative Anaplastic Large Cell Lymphoma: a Case Report and Discussion of Possible Pathogenesis
International Journal of Clinical and Experimental Pathology.
6:1631-1642
2013
Cd40 Exon 8 Deficiency Causes a Novel Form of Immunodeficiency With Hyper-Igm
Journal of Immunology.
190
2013
Direct reprogramming of fibroblasts to myocytes via bacterial injection of MyoD protein.
Cellular reprogramming.
15(2):117-25
[DOI] 10.1089/cell.2012.0058.
[PMID] 23438194.
2013
Genetically Reprogrammed, Liver-Derived Insulin-Producing Cells Are Glucose-Responsive, But Susceptible To Autoimmune Destruction in Settings of Murine Model of Type 1 Diabetes
American Journal of Translational Research.
5:184-199
2013
High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pichia pastoris.
Protein expression and purification.
91(2):221-7
[DOI] 10.1016/j.pep.2013.08.008.
[PMID] 23978536.
2013
Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells.
Journal of immunology (Baltimore, Md. : 1950).
190(8):3916-27
[DOI] 10.4049/jimmunol.1201880.
[PMID] 23509349.
2013
Novel Autoantigens in Type 1 Diabetes
American Journal of Translational Research.
5:379-392
2013
Novel Detection of Pancreatic and Duodenal Homeobox 1 Autoantibodies (Paa) in Human Sera Using Luciferase Immunoprecipitation Systems (Lips) Assay
International Journal of Clinical and Experimental Pathology.
6:1202-1210
2013
The reprogrammed pancreatic progenitor-like intermediate state of hepatic cells is more susceptible to pancreatic beta cell differentiation.
Journal of cell science.
126(Pt 16):3638-48
[DOI] 10.1242/jcs.124925.
[PMID] 23750005.
2013
Transient receptor potential melastatin 4 channel controls calcium signals and dental follicle stem cell differentiation.
Stem cells (Dayton, Ohio).
31(1):167-77
[DOI] 10.1002/stem.1264.
[PMID] 23081848.
2013
Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions.
Molecular biology of the cell.
24(11):1638-48, S1
[DOI] 10.1091/mbc.E12-12-0891.
[PMID] 23552692.
2012
Characterization and Immunotherapeutic Implication of a Novel Cerebro-Spinal Fluid-Derived Alk-Positive Anaplastic Large Cell Lymphoma Cell Line
Blood.
120
2012
Pleiotropic IFN-dependent and -independent effects of IRF5 on the pathogenesis of experimental lupus.
Journal of immunology (Baltimore, Md. : 1950).
188(8):4113-21
[DOI] 10.4049/jimmunol.1103113.
[PMID] 22422888.
2012
Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulation.
BMC immunology.
13
[DOI] 10.1186/1471-2172-13-46.
[PMID] 22897934.
2011
Bacterial delivery of nuclear proteins into pluripotent and differentiated cells.
PloS one.
6(1)
[DOI] 10.1371/journal.pone.0016465.
[PMID] 21304583.
2010
Distinct regulation of hepatic nuclear factor 1alpha by NKX6.1 in pancreatic beta cells.
The Journal of biological chemistry.
285(16):12181-9
[DOI] 10.1074/jbc.M109.064238.
[PMID] 20106981.
2010
Pancreatic duodenal homeobox 1 protein is a novel beta-cell-specific autoantigen for type I diabetes.
Laboratory investigation; a journal of technical methods and pathology.
90(1):31-9
[DOI] 10.1038/labinvest.2009.116.
[PMID] 19901909.
2010
Reprogramming Liver Cells Into Insulin-Producing Cells By Pancreatic Transcription Factors
Human Gene Therapy.
21
2009
Diverse T-cell differentiation potentials of human fetal thymus, fetal liver, cord blood and adult bone marrow CD34 cells on lentiviral Delta-like-1-modified mouse stromal cells.
Immunology.
128(1 Suppl):e497-505
[DOI] 10.1111/j.1365-2567.2008.03013.x.
[PMID] 19740310.
2009
Treatment of type 1 diabetes with adipose tissue-derived stem cells expressing pancreatic duodenal homeobox 1.
Stem cells and development.
18(10):1399-406
[DOI] 10.1089/scd.2009.0010.
[PMID] 19245309.
2008
Big mac attack: does it play a direct role for monocytes/macrophages in type 1 diabetes?
Diabetes.
57(11):2922-3
[DOI] 10.2337/db08-1007.
[PMID] 18971442.
2008
Hairy Cell Leukemia With Unusual Loss of Cd103 in a Subset of the Neoplastic Population: Immunophenotypic and Cell Cycle Analysis By Flow Cytometry
International Journal of Clinical and Experimental Pathology.
1:381-386
2008
Overcoming immune tolerance against multiple myeloma with lentiviral calnexin-engineered dendritic cells.
Molecular therapy : the journal of the American Society of Gene Therapy.
16(2):269-79
[PMID] 18071334.
2008
Pediatric T-cell post-transplant lymphoproliferative disorder after solid organ transplantation.
Pediatric blood & cancer.
50(2):415-8
[PMID] 17051534.
2008
Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: a novel protein transduction domain-based therapy.
Diabetes.
57(3):757-69
[PMID] 18086901.
2008
Transcription Factor Directed Differentiation of Human Embryonic Stem Cells Into the Pancreatic Endocrine Lineage
Cell Research.
18(S1):S109-S109
[DOI] 10.1038/cr.2008.199.
2007
Assessment of bone marrow plasma cell infiltrates in multiple myeloma: the added value of CD138 immunohistochemistry.
Human pathology.
38(12):1779-87
[PMID] 17714757.
2006
Liver stem cell-derived beta-cell surrogates for treatment of type 1 diabetes.
Autoimmunity reviews.
5(6):409-13
[PMID] 16890895.
2004
DRAQ5-based DNA content analysis of hematolymphoid cell subpopulations discriminated by surface antigens and light scatter properties.
Cytometry. Part B, Clinical cytometry.
58(1):47-52
[PMID] 14994375.
2003
Gene expression profiling during all-trans retinoic acid-induced cell differentiation of acute promyelocytic leukemia cells.
The Journal of molecular diagnostics : JMD.
5(4):212-21
[PMID] 14573779.
2002
In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells.
Proceedings of the National Academy of Sciences of the United States of America.
99(12):8078-83
[PMID] 12048252.
Grants
Sep 2017
ACTIVE
PATHOGENESIS OF PRISTANE-INDUCED LUPUS
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Sep 2016
– Aug 2020
Facilitation of stem cell differentiation in severely injured salivary glands
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDCR
Jul 2015
– Dec 2017
Engineering Irisin for Understanding its Benefits to Obestiy
Role: Project Manager
Funding: US ARMY MED RES ACQUISITION
Feb 2014
– Jan 2018
Bone marrow stem cell niche dysfunction in human SLE
Role: Principal Investigator
Funding: LUPUS RES INST
Sep 2011
– Aug 2017
Pathogenesis of Autoantibodies in Pristane-Induced Lupus
Role: Project Manager
Funding: NATL INST OF HLTH NIAMS
Contact Details
Phones:
- Business:
- (352) 265-0071
Emails:
- Business:
- yanglj@pathology.ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100275
GAINESVILLE FL 32610 - Business Street:
-
D6-18 DENTAL SCIENCE BUILDING
GAINESVILLE FL 32610