Lijun Yang,
PROFESSOR
Teaching Profile
Courses Taught
2011-2018,2020-2023
DEN6350 General Pathology
2018
GMS7979 Advanced Research
Board Certifications
-
Lijun YangHematopathology
-
Lijun YangClinical Pathology
-
Lijun YangAnatomic Pathology
Clinical Profile
Specialties
- Pathology, Immunology and Laboratory Medicine
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-0522-3292
Publications
2023
Expression and secretion of glycosylated barley oxalate oxidase in Pichia pastoris.
PloS one.
18(5)
[DOI] 10.1371/journal.pone.0285556.
[PMID] 37167324.
2021
Classical Hodgkin Lymphoma Presenting as a Sigmoid Mass.
Gastroenterology research.
14(3):204-208
[DOI] 10.14740/gr1409.
[PMID] 34267838.
2021
GLP-1 Induces the Expression of FNDC5 Derivatives That Execute Lipolytic Actions.
Frontiers in cell and developmental biology.
9
[DOI] 10.3389/fcell.2021.777026.
[PMID] 34869379.
2020
Recent Updates of Irisin’s Anti-Obesity Research
Journal of Diabetes & Metabolism.
11(4)
[DOI] 10.35248/2155-6156.20.11.843.
2019
Effects of irisin on the differentiation and browning of human visceral white adipocytes.
American journal of translational research.
11(12):7410-7421
[PMID] 31934288.
2018
Clinicopathologic Features and Prognostic Impact of Lymph Node Involvement in Patients With Breast Implant-associated Anaplastic Large Cell Lymphoma.
The American journal of surgical pathology.
42(3):293-305
[DOI] 10.1097/PAS.0000000000000985.
[PMID] 29194092.
2018
Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages.
Frontiers in immunology.
9
[DOI] 10.3389/fimmu.2018.00135.
[PMID] 29456535.
2018
Primary Gastric EBV-positive Diffuse Large B Cell Lymphoma (DLBCL) of the Elderly with Plasmablastic Differentiation.
In vivo (Athens, Greece).
32(2):413-417
[PMID] 29475930.
2017
Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity.
Proceedings of the National Academy of Sciences of the United States of America.
114(34):8980-8985
[DOI] 10.1073/pnas.1706894114.
[PMID] 28784797.
2017
Pathogenesis of Diffuse Alveolar Hemorrhage in Murine Lupus.
Arthritis & rheumatology (Hoboken, N.J.).
69(6):1280-1293
[DOI] 10.1002/art.40077.
[PMID] 28217966.
2016
“Lupoid hepatitis” in SLE patients and mice with experimental lupus.
Clinical immunology (Orlando, Fla.).
172:65-71
[DOI] 10.1016/j.clim.2016.07.007.
[PMID] 27430519.
2016
A Novel Mechanism for Generating the Interferon Signature in Lupus: Opsonization of Dead Cells by Complement and IgM.
Arthritis & rheumatology (Hoboken, N.J.).
68(12):2917-2928
[DOI] 10.1002/art.39781.
[PMID] 27274010.
2016
Angiopoietin-like protein 8 (betatrophin) is a stress-response protein that down-regulates expression of adipocyte triglyceride lipase.
Biochimica et biophysica acta.
1861(2):130-137
[DOI] 10.1016/j.bbalip.2015.11.003.
[PMID] 26569053.
2016
Cell-Permeable Peptide Blocks Tlr4 Signaling and Improves Islet Allograft Survival
Cell Transplantation.
25(7):1319-1329
[DOI] 10.3727/096368916X690449.
2016
Irisin exerts dual effects on browning and adipogenesis of human white adipocytes.
American journal of physiology. Endocrinology and metabolism.
311(2):E530-41
[DOI] 10.1152/ajpendo.00094.2016.
[PMID] 27436609.
2016
Irisin Inhibits Atherosclerosis by Promoting Endothelial Proliferation Through microRNA126-5p.
Journal of the American Heart Association.
5(9)
[PMID] 27671318.
2015
Csf2 and Ptgs2 Epigenetic Dysregulation in Diabetes-prone Bicongenic B6.NODC11bxC1tb Mice.
Genetics & epigenetics.
7:5-17
[DOI] 10.4137/GEG.S29696.
[PMID] 26512207.
2015
Irisin Controls Growth, Intracellular Ca2+ Signals, and Mitochondrial Thermogenesis in Cardiomyoblasts
PLOS ONE.
10(8)
[DOI] 10.1371/journal.pone.0136816.
[PMID] 26305684.
2015
Maintenance of autoantibody production in pristane-induced murine lupus.
Arthritis research & therapy.
17
[DOI] 10.1186/s13075-015-0886-9.
[PMID] 26717913.
2015
Mechanisms of autoantibody production in systemic lupus erythematosus.
Frontiers in immunology.
6
[DOI] 10.3389/fimmu.2015.00228.
[PMID] 26029213.
2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis
Cell Death & Differentiation.
22(9):1437-1450
[DOI] 10.1038/cdd.2014.230.
[PMID] 25613378.
2015
Pancreatic and duodenal homeobox gene 1 (Pdx1) down-regulates hepatic transcription factor 1 alpha (HNF1α) expression during reprogramming of human hepatic cells into insulin-producing cells.
American journal of translational research.
7(6):995-1008
[PMID] 26279745.
2014
Bacterial delivery of TALEN proteins for human genome editing.
PloS one.
9(3)
[DOI] 10.1371/journal.pone.0091547.
[PMID] 24618838.
2014
Histamine-induced Ca2+ signalling is mediated by TRPM4 channels in human adipose-derived stem cells
Biochemical Journal.
463(1):123-134
[DOI] 10.1042/bj20140065.
2014
Irisin Promotes Human Umbilical Vein Endothelial Cell Proliferation through the ERK Signaling Pathway and Partly Suppresses High Glucose-Induced Apoptosis
PLoS ONE.
9(10)
[DOI] 10.1371/journal.pone.0110273.
[PMID] 25338001.
2014
Irisin stimulates browning of white adipocytes through mitogen-activated protein kinase p38 MAP kinase and ERK MAP kinase signaling.
Diabetes.
63(2):514-25
[DOI] 10.2337/db13-1106.
[PMID] 24150604.
2014
Phenotypic Consequences of Tlr7-Driven Interferon and Proinflammatory Cytokine Production in Lupus
Arthritis Research & Therapy.
16(1)
2014
Toll-like receptor 7-stimulated tumor necrosis factor α causes bone marrow damage in systemic lupus erythematosus.
Arthritis & rheumatology (Hoboken, N.J.).
66(1):140-51
[DOI] 10.1002/art.38189.
[PMID] 24449581.
2013
Breast Implant-Associated Alk-Negative Anaplastic Large Cell Lymphoma: a Case Report and Discussion of Possible Pathogenesis
International Journal of Clinical and Experimental Pathology.
6:1631-1642
2013
Cd40 Exon 8 Deficiency Causes a Novel Form of Immunodeficiency With Hyper-Igm
Journal of Immunology.
190
2013
Genetically Reprogrammed, Liver-Derived Insulin-Producing Cells Are Glucose-Responsive, But Susceptible To Autoimmune Destruction in Settings of Murine Model of Type 1 Diabetes
American Journal of Translational Research.
5:184-199
2013
High level expression, efficient purification and bioactivity assay of recombinant human platelet-derived growth factor AA dimer (PDGF-AA) from methylotrophic yeast Pichia pastoris.
Protein expression and purification.
91(2):221-7
[DOI] 10.1016/j.pep.2013.08.008.
[PMID] 23978536.
2013
Novel Autoantigens in Type 1 Diabetes
American Journal of Translational Research.
5:379-392
2013
Novel Detection of Pancreatic and Duodenal Homeobox 1 Autoantibodies (Paa) in Human Sera Using Luciferase Immunoprecipitation Systems (Lips) Assay
International Journal of Clinical and Experimental Pathology.
6:1202-1210
2013
Transient receptor potential melastatin 4 channel controls calcium signals and dental follicle stem cell differentiation.
Stem cells (Dayton, Ohio).
31(1):167-77
[DOI] 10.1002/stem.1264.
[PMID] 23081848.
2012
Characterization and Immunotherapeutic Implication of a Novel Cerebro-Spinal Fluid-Derived Alk-Positive Anaplastic Large Cell Lymphoma Cell Line
Blood.
120
2012
In vitro generation of functional insulin-producing cells from human bone marrow-derived stem cells, but long-term culture running risk of malignant transformation.
American journal of stem cells.
1(2):114-127
[PMID] 22833839.
2010
Distinct regulation of hepatic nuclear factor 1alpha by NKX6.1 in pancreatic beta cells.
The Journal of biological chemistry.
285(16):12181-9
[DOI] 10.1074/jbc.M109.064238.
[PMID] 20106981.
2010
Expression, purification, and characterization of recombinant human pancreatic duodenal homeobox-1 protein in Pichia pastoris.
Protein expression and purification.
72(2):157-61
[DOI] 10.1016/j.pep.2010.04.004.
[PMID] 20381624.
2010
Reprogramming Liver Cells Into Insulin-Producing Cells By Pancreatic Transcription Factors
Human Gene Therapy.
21
2009
Treatment of type 1 diabetes with adipose tissue-derived stem cells expressing pancreatic duodenal homeobox 1.
Stem cells and development.
18(10):1399-406
[DOI] 10.1089/scd.2009.0010.
[PMID] 19245309.
2008
Hairy Cell Leukemia With Unusual Loss of Cd103 in a Subset of the Neoplastic Population: Immunophenotypic and Cell Cycle Analysis By Flow Cytometry
International Journal of Clinical and Experimental Pathology.
1:381-386
2008
Pediatric T-cell post-transplant lymphoproliferative disorder after solid organ transplantation.
Pediatric blood & cancer.
50(2):415-8
[PMID] 17051534.
2008
Transcription Factor Directed Differentiation of Human Embryonic Stem Cells Into the Pancreatic Endocrine Lineage
Cell Research.
18(S1):S109-S109
[DOI] 10.1038/cr.2008.199.
2006
Derivation of Adipocytes from Human Embryonic Stem Cells
Stem Cells and Development.
14(6)
[DOI] https://doi.org/10.1089/scd.2005.14.671.
2006
Reprogramming liver-stem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors.
Lab Invest.
83-93
[DOI] doi.org/10.1038/labinvest.3700368.
2006
Role of Pax4 in Pdx1-VP16-mediated liver-to-endocrine pancreas transdifferentiation.
Laboratory investigation; a journal of technical methods and pathology.
86(8):829-41
[PMID] 16732298.
2004
DRAQ5-based DNA content analysis of hematolymphoid cell subpopulations discriminated by surface antigens and light scatter properties.
Cytometry. Part B, Clinical cytometry.
58(1):47-52
[PMID] 14994375.
2004
High glucose is necessary for complete maturation of Pdx1-VP16-expressing hepatic cells into functional insulin-producing cells.
Diabetes.
53(12):3168-78
[PMID] 15561947.
2004
In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow.
Diabetes.
53(7):1721-32
[PMID] 15220196.
2003
All-trans-retinoic acid induces CD52 expression in acute promyelocytic leukemia.
Blood.
101(5):1977-80
[PMID] 12393392.
Grants
Sep 2017
– Aug 2023
PATHOGENESIS OF PRISTANE-INDUCED LUPUS
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAMS
Sep 2016
– Aug 2020
Facilitation of stem cell differentiation in severely injured salivary glands
Role: Co-Investigator
Funding: NATL INST OF HLTH NIDCR
Jul 2015
– Dec 2017
Engineering Irisin for Understanding its Benefits to Obestiy
Role: Project Manager
Funding: US ARMY MED RES ACQUISITION
Feb 2014
– Jan 2018
Bone marrow stem cell niche dysfunction in human SLE
Role: Principal Investigator
Funding: LUPUS RES INST
Sep 2011
– Aug 2017
Pathogenesis of Autoantibodies in Pristane-Induced Lupus
Role: Project Manager
Funding: NATL INST OF HLTH NIAMS
Contact Details
Phones:
- Business:
- (352) 265-0071
Emails:
- Business:
- yanglj@pathology.ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100275
GAINESVILLE FL 32610 - Business Street:
-
D6-18 DENTAL SCIENCE BUILDING
GAINESVILLE FL 32610