Xu Zeng

Xu Zeng, M.D., Ph.D.

Clinical Professor

Department: MD-PATHOLOGY-GENERAL
Business Phone: (352) 265-0680
Business Email: xu.zeng@ufl.edu

About Xu Zeng

Xu Zeng MD PhD, is board-certified in anatomic and clinical pathology. Prior to joining the faculty at the University of Florida Department of Pathology, Immunology and Laboratory Medicine as a renal pathologist, he worked for a number of years at several well-known medical institutions, such as Wayne State University, Bostwick Laboratory and Temple University, for a number of years.

After completing an anatomic and clinical pathology residency at Long Island Jewish Medical Center in the New Hyde Park, New York, Dr. Zeng completed a renal pathology fellowship at Johns Hopkins Medical Institute in Baltimore Maryland.

In addition to renal pathology, Dr. Zeng’s clinical interests include studying the mechanism of proliferative glomerulonephritis and lupus nephritis.

Accomplishments

Graduate Dean's Award in Ph D in Medical Science
1997 ·

Board Certifications

  • Pathology – Anatomic and Clinical
    American Board of Pathology

Clinical Profile

Specialties
  • Pathology, Immunology and Laboratory Medicine
Subspecialties
  • Anatomic and Clinical Pathology
Areas of Interest
  • Glomerulonephritis

Research Profile

Areas of Interest
  • Mechanisms of proliferative glomerulonephritis and lupus nephritis

Publications

2023
Does kidney biopsy in pediatric lupus patients “complement” the management and outcomes of silent lupus nephritis? Lessons learned from a pediatric cohort.
Pediatric nephrology (Berlin, Germany). 38(8):2669-2678 [DOI] 10.1007/s00467-022-05859-w. [PMID] 36688943.
2023
Synthetic cannabinoid-associated acute interstitial nephritis: An emerging cause of pediatric acute kidney injury?
Clinical nephrology. Case studies. 11:55-60 [DOI] 10.5414/CNCS111063. [PMID] 37006641.
2022
Drug-Induced Lupus Secondary to Ethosuximide in Association with Acute Tubulointerstitial Nephritis and Nephrotic Syndrome.
Pediatric reports. 14(2):190-199 [DOI] 10.3390/pediatric14020026. [PMID] 35466205.
2022
Immune checkpoint inhibitor associated renally limited thrombotic microangiopathy – a clinical dilemma
European Journal of Cancer. 169:126-130 [DOI] 10.1016/j.ejca.2022.03.031.
2021
Collapsing Focal Segmental Glomerulosclerosis and Acute Kidney Injury Associated With Chimeric Antigen Receptor T-Cell (CAR-T) Therapy: A Case Report.
Kidney medicine. 3(6):1086-1090 [DOI] 10.1016/j.xkme.2021.06.011. [PMID] 34939018.
2021
Concomitant nephrotic syndrome and tubulointerstitial nephritis in a child with Epstein-Barr virus mononucleosis
BMJ Case Reports. 14(2) [DOI] 10.1136/bcr-2020-240108. [PMID] 33541950.
2021
Delayed Onset Minimal Change Disease as a Manifestation of Lupus Podocytopathy.
Clinics and practice. 11(4):747-754 [DOI] 10.3390/clinpract11040089. [PMID] 34698110.
2020
Graft-versus-host disease of the kidney.
Hematology/oncology and stem cell therapy. 13(3):178-179 [DOI] 10.1016/j.hemonc.2019.01.003. [PMID] 30807739.
2019
Kidney injury molecule-1, a sensitive and specific marker for identifying acute proximal tubular injury, can be used to predict renal functional recovery in native renal biopsies
International Urology and Nephrology. 51(12):2255-2265 [DOI] 10.1007/s11255-019-02311-1.
2018
A curious case of antiglomerular basement membrane antibody disease.
Clinical case reports. 6(8):1647-1648 [DOI] 10.1002/ccr3.1677. [PMID] 30147929.
2018
Acute interstitial nephritis: a multifaceted disease.
Clinical case reports. 6(5):946-947 [DOI] 10.1002/ccr3.1456. [PMID] 29744094.
2018
Detection of recurrent membranous nephropathy in a renal allograft by biomarker
Advances in Cytology & Pathology. 3(3) [DOI] 10.15406/acp.2018.03.00054.
2018
Emphysematous pyelonephritis.
Clinical case reports. 6(2):439-441 [DOI] 10.1002/ccr3.1364. [PMID] 29445494.
2018
Idiopathic membranoproliferative glomerulonephritis treated with mycophenolate mofetil.
Clinical case reports. 6(11):2287-2288 [DOI] 10.1002/ccr3.1826. [PMID] 30455941.
2018
Not all inflammation in a renal allograft is rejection.
Clinical case reports. 6(11):2285-2286 [DOI] 10.1002/ccr3.1825. [PMID] 30455940.
2018
Renal cyst infection: a diagnostic dilemma.
Clinical case reports. 6(4):762-763 [DOI] 10.1002/ccr3.1441. [PMID] 29636958.
2018
Rituximab therapy for hepatitis C virus-associated cryoglobulinemic membranoproliferative glomerulonephritis.
Clinical case reports. 6(2):442-443 [DOI] 10.1002/ccr3.1371. [PMID] 29445495.
2018
Silent Acute Interstitial Nephritis: Suspicion Is the Key to Diagnosis.
The American journal of medicine. 131(4):e151-e152 [DOI] 10.1016/j.amjmed.2017.11.016. [PMID] 29203249.
2018
Two transplant renal arteries: One important lesson.
Clinical case reports. 6(9):1909-1910 [DOI] 10.1002/ccr3.1736. [PMID] 30214795.
2017
Acute interstitial nephritis and DRESS syndrome without eosinophilia associated with cefepime.
BMJ case reports. 2017 [DOI] 10.1136/bcr-2017-221401. [PMID] 28775112.
2017
ANCA-positive IgA nephropathy without necrotising or crescentic glomerulonephritis: a clinical conundrum.
BMJ case reports. 2017 [DOI] 10.1136/bcr-2017-222171. [PMID] 29170179.
2016
Administration of Vasoconstrictor, But Not Volume Expander Prevents Maternal Hypotension During Spinal-Epidural Anesthesia For Elective Cesarean Section
SAJ Case Reports. 3(1):1-8 [DOI] 10.18875/2375-7043.3.102.
2016
Nephropathy Associated With Prolong Lithium Administration
SAJ Case Reports. 3(1):1-4 [DOI] 10.18875/2375-7043.3.103.
2016
Nivolumab-associated acute glomerulonephritis: a case report and literature review.
BMC nephrology. 17(1) [PMID] 27876011.
2015
C1q Nephropathy: The Unique Underrecognized Pathological Entity
Analytical Cellular Pathology. 2015:1-5 [DOI] 10.1155/2015/490413. [PMID] 26640759.
2015
Immunotactoid Glomerulopathy and Cryoglobulinemic Nephropathy: Two Entities with Many Similarities. A Unified Conceptual Approach
Ultrastructural Pathology. 39(4):270-280 [DOI] 10.3109/01913123.2015.1017070.
2015
Proximal Tubular Injury in Medullary Rays Is an Early Sign of Acute Tacrolimus Nephrotoxicity
Journal of Transplantation. 2015:1-6 [DOI] 10.1155/2015/142521. [PMID] 26199736.
2014
Henoch-SchÖlein Purpura Nephritis in Children: A Severe IgA Mediated Glomerulonephritis
SAJ Case Reports. 1(2) [DOI] 10.18875/2375-7043.1.201.
2014
Lupus vasculopathy: Diagnostic, pathogenetic and therapeutic considerations.
Lupus. 23(4):421-7 [DOI] 10.1177/0961203313520340. [PMID] 24452079.
2014
Participation of Functionally Active Plasma Cells in Acute Rejection and Response to Therapy in Renal Allografts
DNA and Cell Biology. 33(7):448-454 [DOI] 10.1089/dna.2014.2371.
2014
Plasma exchange for concurrent lupus nephritis and antiphospholipid syndrome
Clinical Kidney Journal. 7(1):86-89 [DOI] 10.1093/ckj/sft150. [PMID] 25859362.
2014
The Many Faces of Cryoglobulinemic Nephropathy: A Clinico-Pathologic Study of 47 Cases with Emphasis on the Value of Electron Microscopy
Ultrastructural Pathology. 38(6):367-376 [DOI] 10.3109/01913123.2014.952803.
2014
Urinary β2-Microglobulin Is a Good Indicator of Proximal Tubule Injury: A Correlative Study with Renal Biopsies
Journal of Biomarkers. 2014:1-7 [DOI] 10.1155/2014/492838. [PMID] 26317034.
2014
Urinary β2-Microglobulin is a Sensitive Indicator for Renal Tubular Injury
SAJ Case Reports. 1(1) [DOI] 10.18875/2375-7043.1.103.
2013
Fibrillary glomerulonephritis in a patient with systemic lupus erythematosus: a rare association.
International urology and nephrology. 45(1):281-4 [DOI] 10.1007/s11255-011-0073-0. [PMID] 22102086.
2012
The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats
Mediators of Inflammation. 2012:1-8 [DOI] 10.1155/2012/692467. [PMID] 22619485.
2010
Predictors of end stage renal disease in African Americans with lupus nephritis.
Bulletin of the NYU hospital for joint diseases. 68(4):251-6 [PMID] 21162701.
2009
Fibrillary glomerulonephritis and renal failure in a child with systemic lupus erythematosus.
Pediatric nephrology (Berlin, Germany). 24(8):1577-81 [DOI] 10.1007/s00467-009-1168-z. [PMID] 19308460.
2009
Million Man March
African American Studies Center. [DOI] 10.1093/acref/9780195301731.013.45906.
2007
Intermediate-term outcomes with early steroid withdrawal in African-American renal transplant recipients undergoing surveillance biopsy.
Surgery. 142(4):538-44; discussion 544 [PMID] 17950346.
2003
Role of protein kinase A in GABAA receptor dysfunction in CA1 pyramidal cells following chronic benzodiazepine treatment.
Journal of neurochemistry. 85(4):988-98 [PMID] 12716430.
2000
Role of bicarbonate ion in mediating decreased synaptic conductance in benzodiazepine tolerant hippocampal CA1 pyramidal neurons.
Brain research. 868(2):202-14 [PMID] 10854572.
1999
Antagonist-induced reversal of functional and structural measures of hippocampal benzodiazepine tolerance.
The Journal of pharmacology and experimental therapeutics. 291(3):932-42 [PMID] 10565808.
1999
Benzodiazepine tolerance at GABAergic synapses on hippocampal CA1 pyramidal cells.
Synapse (New York, N.Y.). 31(4):263-77 [PMID] 10051107.
1999
Benzodiazepine-mediated regulation of alpha1, alpha2, beta1-3 and gamma2 GABA(A) receptor subunit proteins in the rat brain hippocampus and cortex.
Neuroscience. 93(1):33-44 [PMID] 10430468.
1997
Depression of early and late monosynaptic inhibitory postsynaptic potentials in hippocampal CA1 neurons following prolonged benzodiazepine administration: role of a reduction in Cl- driving force.
Synapse (New York, N.Y.). 25(2):125-36 [PMID] 9021893.
1995
Reduction of GABA-mediated inhibitory postsynaptic potentials in hippocampal CA1 pyramidal neurons following oral flurazepam administration.
Neuroscience. 66(1):87-99 [PMID] 7637878.
1994
Impairment of feedforward inhibition in CA1 region of hippocampus after chronic benzodiazepine treatment.
Neuroscience letters. 173(1-2):40-4 [PMID] 7936420.
Henoch-Schonlein Purpura nephritis in association with cirrhotic Wilson disease in a child. Clinical Nephrology-Case Studies, Vol. 8/2020 (80-84).
.
Impact of HLA antibody monitoring and Kidney Transplantation. Clinical Transplant 2014 chapter 18:143-151
.
Kidney injury molecule-1 is a sensitive and specific marker of acute tubular injury in pediatric renal biopsy. J Transplantation. 2014
.
nPOD-Kidney, a heterogenous donor cohort for the investigation of diabetic kidney disease pathogenesis and progression. NIH publications, May, 2022
.

Education

Fellowship
2005 · Johns Hopkins Medical Institute
Residency
2004 · Long Island Jewish Medical Center
M.D.
1985 · Guangzhou Medical College

Contact Details

Phones:
Business:
(352) 265-0680
Emails:
Business:
xu.zeng@ufl.edu
Addresses:
Business Mailing:
PO Box 100275
GAINESVILLE FL 32610