PGX
Cardiology
| Drug Class | Drug | Gene |
|---|---|---|
| Antiplatelet Agent | Clopidogrel (Plavix®) | CYP2C19 |
Gastroenterology
| Drug Class | Drug | Gene |
|---|---|---|
| Proton Pump Inhibitors (PPIs) | Dexlansoprazole (Dexilant®) | CYP2C19 |
| Esomeprazole (Nexium®) | CYP2C19 | |
| Lansoprazole (Prevacid®) | CYP2C19 | |
| Omeprazole (Prilosec®) | CYP2C19 | |
| Pantoprazole (Protonix®) | CYP2C19 | |
| Rabeprazole (Aciphex®) | CYP2C19 | |
| Antiemetics | Ondansetron (Zofran®) | CYP2D6 |
| Tropisetron (Navoban®) | CYP2D6 |
Hematology/Oncology
| Drug Class | Drug | Gene |
|---|---|---|
| Thiopurine | Azathioprine (Imuran®) | TPMT |
| Mercaptopurine (Purixan®) | TPMT | |
| Thioguanine (Tabloid®) | TPMT | |
| Selective Estrogen Receptor Modulator (SERM) | Tamoxifen (Soltamox®) | CYP2D6 |
Infectious Diseases
| Drug Class | Drug | Gene |
|---|---|---|
| Antifungal | Voriconazole (Vfend®) | CYP2C19 |
Pain Management
| Drug Class | Drug | Gene |
|---|---|---|
| Opioids | Codeine (Codeine®) | CYP2D6 |
| Codeine/Acetaminophen (Tylenol #3, #4®) | CYP2D6 | |
| Hydrocodone/Acetaminophen (Vicodin®) | CYP2D6 | |
| Oxycodone (Oxycontin®) | CYP2D6 | |
| Oxycodone/Acetaminophen (Percocet®) | CYP2D6 | |
| Oxycodone/Naloxone (Targiniq ER®) | CYP2D6 | |
| Tramadol (Ultram®) | CYP2D6 | |
| Tramadol hydrochloride/Acetaminophen (Ultracet®) | CYP2D6 |
Psychiatry
| Drug Class | Drug | Gene |
|---|---|---|
| Selective Serotonin Reuptake Inhibitors (SSRIs) | Citalopram (Celexa®) | CYP2C19 |
| Escitalopram (Lexapro®) | CYP2C19 | |
| Fluvoxamine (Luvox®) | CYP2D6 | |
| Paroxetine (Paxil®) | CYP2D6 | |
| Sertraline (Zoloft®) | CYP2C19 | |
| Tricyclic Antidepressants | Amitriptyline (Elavil®) | CYP2C19, CYP2D6 |
| Clomipramine (Anafranil®) | CYP2C19, CYP2D6 | |
| Desipramine (Norpramin®) | CYP2D6 | |
| Doxepin (Silenor®) | CYP2C19, CYP2D6 | |
| Imipramine (Tofranil®) | CYP2C19, CYP2D6 | |
| Nortriptyline (Pamelor®) | CYP2D6 | |
| Trimipramine (Surmontil®) | CYP2C19, CYP2D6 |