PGX

Cardiology

Drug Class Drug Gene
Antiplatelet Agent Clopidogrel (Plavix®) CYP2C19

Gastroenterology

Drug Class Drug Gene
Proton Pump Inhibitors (PPIs) Dexlansoprazole (Dexilant®) CYP2C19
Esomeprazole (Nexium®) CYP2C19
Lansoprazole (Prevacid®) CYP2C19
Omeprazole (Prilosec®) CYP2C19
Pantoprazole (Protonix®) CYP2C19
Rabeprazole (Aciphex®) CYP2C19
Antiemetics Ondansetron (Zofran®) CYP2D6
Tropisetron (Navoban®) CYP2D6

Hematology/Oncology

Drug Class Drug Gene
Thiopurine Azathioprine (Imuran®) TPMT
Mercaptopurine (Purixan®) TPMT
Thioguanine (Tabloid®) TPMT
Selective Estrogen Receptor Modulator (SERM) Tamoxifen (Soltamox®) CYP2D6

Infectious Diseases

Drug Class Drug Gene
Antifungal Voriconazole (Vfend®) CYP2C19

Pain Management

Drug Class Drug Gene
Opioids Codeine (Codeine®) CYP2D6
Codeine/Acetaminophen (Tylenol #3, #4®) CYP2D6
Hydrocodone/Acetaminophen (Vicodin®) CYP2D6
Oxycodone (Oxycontin®) CYP2D6
Oxycodone/Acetaminophen (Percocet®) CYP2D6
Oxycodone/Naloxone (Targiniq ER®) CYP2D6
Tramadol (Ultram®) CYP2D6
Tramadol hydrochloride/Acetaminophen (Ultracet®) CYP2D6

Psychiatry

Drug Class Drug Gene
Selective Serotonin Reuptake Inhibitors (SSRIs) Citalopram (Celexa®) CYP2C19
Escitalopram (Lexapro®) CYP2C19
Fluvoxamine (Luvox®) CYP2D6
Paroxetine (Paxil®) CYP2D6
Sertraline (Zoloft®) CYP2C19
Tricyclic Antidepressants Amitriptyline (Elavil®) CYP2C19, CYP2D6
Clomipramine (Anafranil®) CYP2C19, CYP2D6
Desipramine (Norpramin®) CYP2D6
Doxepin (Silenor®) CYP2C19, CYP2D6
Imipramine (Tofranil®) CYP2C19, CYP2D6
Nortriptyline (Pamelor®) CYP2D6
Trimipramine (Surmontil®) CYP2C19, CYP2D6