1p/19q, d(1;19) Deletion by FISH

CPT Code(s):

88365, 88364

Specimen Requirements:

Collection: Tumor tissue

Storage/Transport Temperature: Specimens should be formalin-fixed, paraffin-embedded and stored between 20° – 25° C; paraffin blocks should be protected from excessive heat. Specimens should be shipped in a cooled container during summer months. A surgical pathology report should be included with all shipped specimens.ort should be included with all shipped specimens.

Unacceptable Conditions:
  • Tissue without tumor cells
  • Frozen specimens
  • Specimens processed in any fixative other than formalin
Stability (collection to initiation of testing):
  • Ambient: Indefinitely
  • Frozen: Unacceptable


The loss of presence of these chromosomes and genes indicates the presence of an oligodendroglioma but does not conclude an oligodendroglioma.


Fluorescence in situ hybridization


Within 9 days

Reference Values:

Non-deleted; interpretive report.