Adrenocortical Autoantibodies

Additional Information:

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CPT Code(s):

88347

Collection Procedure:

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Specimen Requirements:

Collect blood in a 1- 5 mL serum separator tube. Centrifuge, separate and transfer the serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.

Stability (collection to shipping of the sample):

  • Ambient: 24 hours
  • Refrigerated: 24 hours
  • Frozen: 1 year (Avoid repeated freeze/thaw cycles.)

Use:

  • Diagnosis of Addison’s Disease: Adrenocortical cytoplasmic autoantibodies detected in the presence of biochemically defined primary adrenocortical insufficiency identify an autoimmune etiology as the cause of the subject’s Addison’s disease (e.g., autoimmune Addison’s disease).
  • Prediction of Addison’s Disease: Adrenocortical cytoplasmic autoantibodies detected in an asymptomatic individual indicate an increased risk for the subsequent development of clinical Addison’s disease.

Methodology:

Indirect immunofluorescence

Reported:

1 - 7 business days

Reference Values:

Negative interpretive report

Performed:

Weekly

Interpretation Data:

-