Anti-Beta-2 Glycoprotein 1 Antibodies, IgG & IgM
EPIC Test Name: BETA-2 GLYCOPROTEIN ANTIBODIES
UFHPL Epic order code: LAB1179
Type: Plasma (preferred) or Serum
Container/Tube: Sodium Citrate (Light Blue Top) or SST
Sample Volume: 1 mL
Minimum Volume: 0.1 mL (Repeat testing is not possible with this specimen volume.)
Storage: Centrifuge, separate and transfer the plasma or serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.
Stability (collection to time of analysis/testing):
- Refrigerated: 48 hours
- Frozen: 1 year
This assay is used in the diagnosis of antiphospholipid
Vascular Thrombosis: One or more clinical episodes of arterial, venous or small-vessel thrombosis in any
tissue or organ.
- One or more unexplained deaths of a morphologically normal fetus at or beyond the tenth week of gestation, with normal fetal morphology documented by ultrasound.
- One or more premature births of a morphologically normal neonate before the 34th week of gestation because of (a) eclampsia or severe preeclampsia divined according to standard definitions or (b) recognized features of placental insufficiency.
- Three or more unexplained consecutive spontaneous abortions before the tenth week of gestation, with maternal anatomic or hormonal abnormalities and paternal and maternal chromosomal causes excluded.
- Anti-β2 glycoprotein-I antibody of IgG and/or IgM isotype in serum or plasma (in titer > the 99th percentile)
Enzyme- linked immunosorbent assay (ELISA)
1-7 Business Days
- β2 GPI IgG ≤ 20 SGU U/mL
- β2 GPI IgM ≤ 20 SMU U/mL
- β2 GPI IgG > 20 SGU U/mL
- β2 GPI IgM > 20 SMU U/mL