Anti-Cardiolipin Antibodies, IgG & IgM

Additional Information:


EPIC Test Name: CARDIOLIPIN ANTIBODY
EPIC order code: LAB4799

CPT Code(s):


86147 x 2

Collection Procedure:


Collect specimen in light blue top sodium citrate tube. Store refrigerated. Transport to lab.

Specimen Requirements:


Specimen Type: Plasma (preferred) or Serum
Container/Tube: Sodium Citrate (Light Blue Top) or SST
Sample Volume: 1 mL
Minimum Volume: 0.1 mL (Repeat testing is not possible with this specimen volume.)
Storage:Refrigerate
Stability (collection to time of analysis/testing):

  • Refrigerated: 48 hours
  • Frozen: 1 year

Use:

This test is used to diagnose antiphospholipid syndrome.

Vascular Thrombosis: One or more clinical episodes of arterial, venous or small-vessel thrombosis in any tissue or organ

Pregnancy Morbidity:

  • One or more unexplained deaths of a morphologically normal fetus at or beyond the tenth week of gestation, with normal fetal morphology documented by ultrasound
  • One or more premature births of a morphologically normal neonate before the 34th week of gestation because of (a) eclampsia or severe preeclampsia divined according to standard definitions or (b) recognized features of placental insufficiency
  • Three or more unexplained consecutive spontaneous abortions before the tenth week of gestation, with maternal anatomic or hormonal abnormalities and paternal and maternal chromosomal causes excluded

Methodology:


Enzyme-Linked Immunosorbent Assay (ELISA)

Reported:


1-7 Business Days

Reference Values:

  • Normal:
    • IgG < 15 GPL U/mL
    • IgM < 12.5 MPL U/mL
  • Indeterminate:
    • IgG = 15 – 20 GPL U/mL
    • IgM = 12.5 – 20 MPL U/mL
  • Positive:
    • IgG > 20 GPL U/mL
    • IgM > 20 MPL U/mL