Cell Culture: Solid Tissue Only

CPT Code(s):

88329 per routine test

Specimen Requirements:

Skin Biopsy: In an aseptic manner, obtain an approximately 2 mm x 2 mm specimen, which is deep enough to ensure that the dermal layer is included. Deposit the specimen in a sterile container that contains the tissue culture medium with antibiotics, which has been brought to room temperature prior to collection. Alternate solid tissue samples include autopsy specimens (e.g., lung, cartilage, etc.).

Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 – 48 hours. Ship specimens at room temperature for overnight delivery.


This test is used for esoteric send-out testing, which may require a given quantity of cells or living tissuecultures (e.g., specific enzyme test for metabolic disorders, etc.).


Cell culture for cell-line buildup only; for reference lab send-out


14 – 21 days

Reference Values:

By report; interpretive