Chromosome Study: Chorionic Villi
Chorionic Villi: Collect 10 - 30 mg of chorionic villi, utilizing aspiration medium, containing sodium heparin. After assessment of the appropriate amount and quality of villi, transfer it to a sterile centrifuge tube with a transportation medium.
Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 - 48 hours. Ship specimens at room temperature for overnight delivery.
- Unacceptable Conditions:
- Frozen specimens
- Specimens greater than 48 hours old*
- Stability (collection to initiation of testing):
- Ambient: 24 - 48 hours old*
- Frozen: Unacceptable
* Cell viability of specimens requiring cell culture may be compromised in specimens more than 48 hours old upon receipt. Refrigeration at 2° - 8° C may assist when a delay in delivery is unpreventable. Do not freeze or place specimens directly on ice.
This test is used to detect fetal chromosome abnormalities at 11 - 15 weeks of gestation.
Classic cytogenetic G-band analysis (karyotyping); requires cell culture
10 - 14 days
By report; interpretive
Monday - Saturday