Chromosome Study: Neoplastic Lymphatic Tissue
Lymph Node/Spleen/Other: Aseptically obtain a sample of approximately 2 mm x 2 mm x 2 mm and deposit it in RPMI tissue culture medium.*
Fine-Needle Aspirates: Deliver the contents in RPMI or sterile tissue culture medium in a 15 mL conical tube.*
- Frozen specimens
- Specimens greater than 48 hours old*
- Ambient: 24 - 48 hours old*
- Frozen: Unacceptable
* Cell viability of specimens requiring cell culture may be compromised in specimens greater than 48 hours old upon receipt. Refrigeration at 2° - 8° C may assist when a delay in delivery is unpreventable. Do not freeze or place specimens directly on ice.
No formalin-, alcohol- or paraffin-preserved specimens. Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 - 48 hours. Ship specimens at room temperature for overnight delivery.
This test is used to identify clonal chromosome changes by conventional karyotyping methods associated with various lymphoma subtypes.
Classic cytogenetic G-band analysis (karyotyping); requires cell culture
7 - 21 days
By report; interpretive
Monday - Saturday