Chromosome Study: Neoplastic Solid Tumor

Additional Information:

UFHPL Epic order code: LAB5851

CPT Code(s):

  • 88239
  • 88262
  • 88291

Specimen Requirements:

Solid Tumor Tissue: Aseptically obtain a sample (approximately 2 mm x 2 mm x 2 mm) and deposit it in RPMI or tissue culture medium.*

Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 – 48 hours. Ship specimens at room temperature for overnight delivery.

Unacceptable Conditions:

  • Frozen specimens
  • Formalin, alcohol, or paraffin-preserved specimens
Stability (collection to initiation of testing):

  • Ambient: 24 – 48 hours old*
  • Frozen: Unacceptable

* Cell viability of specimens requiring cell culture may be compromised in specimens greater than 48 hours old upon receipt. Refrigeration at 2° – 8° C may assist when a delay in delivery is unpreventable. Do not freeze or place specimens directly on ice.


This test is used to detect clonal cytogenetic changes in solid tumor tissue specimens which may provide classification and prognostic information.


Classic cytogenetic G-band analysis (karyotyping); requires cell culture


10 – 28 days

Reference Values:

By report; interpretive