Chromosome Study: Routine Peripheral Blood
Peripheral Blood: Peripheral blood must be collected aseptically in sodium heparin tubes (usually greentop tubes) and immediately rotated thoroughly to prevent clotting; for infants, obtain approximately 2 cc, and obtain 5 - 7 cc for children and adults.
Note: A separate blood sample is required if concurrent CGH microarray study is desired.
Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 - 48 hours. Ship specimens at room temperature for overnight delivery.
- Frozen specimens
- Specimens greater than 48 hours old*
- Ambient: 24 - 48 hours old*
- Frozen: Unacceptable
* Cell viability of specimens requiring cell culture may be compromised in specimens greater than 48 hours old upon receipt. Refrigeration at 2° - 8° C may assist when a delay in delivery is unpreventable. Do not freeze or place specimens directly on ice.
This test is used to assess the karyotypic status in individuals with phenotypic abnormalities who are suspected to have congenital chromosome abnormality (e.g., down syndrome or trisomy 21) and/or be a carrier of a chromosome abnormality by clinical or family history.
Classic cytogenetic G-band analysis (karyotyping); requires cell culture
14 - 21 days
By report; interpretive
Monday - Saturday