Additional Information:
EPIC Test Name: COMPREHENSIVE ENDOCRINE AUTOANTIBODY PANEL
EPIC order code: LAB12300013
This panel includes the following tests:
Adrenal Cortical Autoantibodies
Gastric Parietal Cell Autoantibodies
Glutamic Acid Decarboxylase Autoantibodies (GADA)
Insulin Autoantibodies (IAA)
Insulinoma Associated-2 Autoantibodies (IA-2A)
Islet Cell Autoantibodies
Thyroglobulin Autoantibodies (TGA)
Thyroperoxidase Autoantibodies (TPOA)
Zinc Transporter 8 Autoantibody (ZnT8A)
CPT Code(s):
- 88346
- 88350 (x 2)
- 86341 (x 3)
- 86337
- 86800
- 86376
Specimen Requirements:
Type: Serum
Container/Tube: SST
Sample Volume: 3 mL
Minimum Volume: 1 mL (Repeat testing is not possible with this specimen volume.)
Storage: Centrifuge, separate and transfer the serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.
Stability (collection to time of analysis/testing):
- Refrigerated: 24 hours
- Frozen: 1 year
Use:
- Diagnosis of an Autoimmune Endocrine Disorder: In the presence of clinical endocrine disease, an autoantibody directed against the affected gland indicates an autoimmune etiology for the glandular dysfunction.
- Prediction of an Autoimmune Endocrine Disorder: Endocrine autoantibodies detected in an asymptomatic individual indicate an increased risk for the subsequent development of clinical endocrine disease.
Methodology:
Indirect Immunofluorescence (ICA, Adreno-Cort Ab, Gastric Parietal Ab), Radioimmunoassay (IA-2A, IAA, TGA, TPOA), Enzyme-linked Immunosorbant Assay (GADA, ZnT8A)
Reported:
7-20 days
Reference Values:
ADRENO-CORT AB Ref. Range: Negative
GAST PARIETAL AB Ref. Range: Negative
ISLET CELL ANTIBODY Ref. Range: 0.0, 5.0 JDF
THYROGLOBULIN AB Ref. Range: <1.0 U/mL
THYROID PEROXIDASE ANTIBODIES Ref. Range: <1.0 U/mL
IA2 AUTOANTIBODIES (ISLET) Ref. Range: 0.00-<0.90 U/mL
ZINC T8 AUTOANTIBODY Ref. Range: ≤ 15.0 U/mL
INSULIN AUTOANTIBODY Ref. Range: 0-94 nU/mL
GLUTAMIC ACID DECARBOXYLASE ANTIBODY Ref. Range: <5.0 IU/mL