Epidermal Growth Factor Receptor Mutation Analysis (EGFR Mutation)
Epic order code: LAB5644
- 81235 (needs confirmation)
- 88381 (FFPE)
At least 7 unstained formalin-fixed paraffin-embedded slides with adequate amounts of tumor to be analyzed with the areas of tumor marked.
Storage/Transport: Ship specimens at 20° - 25° C for overnight delivery and protect them from excessive heat. Include a surgical pathology report.
- Specimens that do not contain tumor
- Specimens in fixatives other than 10% formalin
- Frozen specimens
- Ambient: Indefinitely
- Refrigerated: Acceptable
- Frozen: Unacceptable
This test is used to detect EGFR somatic mutations in exons 18, 19, 20 and 21. EGFR mutation is significantly associated with response to gefitinib and erlotinib and prolonged survival in non-small-cell lung carcinoma patients.
Real-time polymerase reaction
Within 10 business days