ER/PR (Estrogen/Progesterone Receptor Image Analysis)

CPT Code(s):

88361 x 2

Specimen Requirements:

At least five unstained slides or a paraffin block containing representative breast tumor

Storage/Transport: Ship at 20 – 25°C, protect from excessive heat. Include surgical pathology report.


This test is used in the diagnosis of patients with invasive breast cancer. Positive results aid in choosing appropriate treatment therapies.


Immunohistochemistry with image quantitation


7 days

Reference Values:

Antibody % Nuclear Area Interpretation
ER < 1% Negative
> 1% Positive
PR < 1% Negative
> 1% Positive