Human Papillomavirus (HPV) Detection, High Risk
- Cervical Brushes: Specimens must be collected prior to the application of acetic acid or iodine if colposcopic examination is being performed. The samples should be collected by using a Digene cervical brush and stored in Digene STM solution.
- Cervical Biopsies: Specimens must be freshly collected, 2 - 5 mm in cross section. The biopsy specimen must be placed immediately into 1.0 mL of STM and stored frozen.
- Specimens in ThinPrep® Cytyc PreservCyt® Solution: There must be at least 4 mL of PreservCyt® solution remaining for the HPV DNA test.
- Specimen in SurePath™ (AutoCyte) Solution: There are must be 2 mL of SurePath™ solution remaining for the HPV DNA test.
Remarks: Vaginal specimens are not preferred.
Handling: Cervical-brush specimens may be shipped without refrigeration to a testing laboratory; however, fresh specimens should be shipped in an insulated container using either an overnight or second-day delivery vendor.
Cervical biopsy specimens may be shipped at 2° - 30° C for overnight delivery to the testing laboratory.
- Frozen specimens
- Swabs or samples in any other transport media
- Ambient: SurePath™; 4 weeks at 15° - 30° C.
- Ambient: Thin Prep® or PreservCyt®; 3 weeks at 15° - 30° C.
The HPV DNA, high-risk test is used in conjunction with liquid-based cytology screenings to detect cervical cancer.
Nucleic acid probe
Negative (interpretative report provided)
Monday - Friday
HPV DNA was detected by using the FDA-approved testing kit, Hybrid Capture 2. The test detects HPV high-risk genotypes: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68.
|Detected|| High-risk HPV DNA was detected in
this patient sample.
|Not Detected|| High-risk HPV DNA was not detected
in this patient sample.
|QNS|| Due to inadequate specimens,
resubmission of samples is suggested.