Islet Cell Cytoplasmic Autoantibodies (ICA)

Additional Information:


EPIC Test Name: ANTI-ISLET CELL AB

This is the same test as UF Health Pathology Laboratories’ assay for Islet Cell Autoantibodies.

CPT Code(s):


88346

Specimen Requirements:


Type: Serum
Container/Tube: SST
Sample Volume: 1 mL
Minimum Volume: 0.2 mL (Repeat testing is not possible with this specimen volume.)
Storage: Centrifuge, separate and transfer the serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.
Stability (collection to time of analysis/testing):

  • Refrigerated: 24 hours
  • Frozen: 1 year

Use:

  • Diagnosis of Type 1 Diabetes: The presence of islet cell cytoplasmic autoantibodies (ICA) in patients with diabetes mellitus indicates the presence of autoimmune, type 1 diabetes.
  • Prediction of Type 1 Diabetes: The presence of islet cell cytoplasmic autoantibodies (ICA) in an asymptomatic individual places the subject at increased risk for the development of type 1 diabetes.

Methodology:


Indirect Immunofluorescence

Reported:


1-10 business days

Reference Values:

Negative (< 5 JDF) (quantitative results reported in JDF units)