KRAS Mutation Detection
Paraffin-embedded, formalin-fixed tissue block
In case the blocks are not available, 5 unstained slides are acceptable. Ship specimens at 20° - 25° C. Tissues not fixed in formalin are unacceptable.
- Frozen specimens
- Specimens in formalin substitute
- Ambient: Indefinitely
This assay is designed to detect mutations in the coding sequence of the KRAS gene. Mutations in this gene are linked to resistance to cancer therapies that target to the KRAS pathway in colorectal and other cancers.
10 - 14 days
No mutation present (normal)
Analytical sensitivity: 5% tumor
Monday - Friday
|Mutation Detected||Pathogenic mutations detected in the KRAS coding sequence will be reported.|
|No Mutation Detected||No KRAS mutation was identified in the provided specimen of this patient.|
|QNS||Due to inadequate specimen or less than 10% tumor cells presents in the tissue|