Levetiracetam (Keppra)

Additional Information:

UFHPL Epic order code: LAB477

CPT Code(s):


Specimen Requirements:

Collect at least 2mL of blood in a plain red-top or lavender-top (EDTA) serology tube. Centrifuge the blood and remove the serum/plasma from the cells within two hours of collection.

Transport/Storage Temperature:

  • Refrigerated
Stability (collection to shipping of the sample):

  • Ambient: 14 days
  • Refrigerated: 14 days
Rejection Criterion:

  • Do not submit specimens in serum-separator tubes (SST), as the gel in the tube may absorb the levetiracetam.


This test is used for the quantitation of levetiracetam, an anti-epileptic drug, in serum/plasma.


Liquid chromatography/Tandem mass spectrometry (LC-MS/MS)


Within 3 days

Reference Values:

10−40 μg/mL