Muscle Pathology

CPT Code(s):

  • 88305
  • 88313 x 2
  • 88314
  • 88319 x 7

Specimen Requirements:

A muscle specimen measuring at least one cubic centimeter (1 cm3) is required for proper evaluation. Submitted specimens should be wrapped in saline-moistened gauze (NOT SOAKED); do not allow the specimen to float in saline.

**Specimens MUST be prepared by carefully following our muscle biopsy shipping instructions. Please watch our Muscle Specimen Collection and Handling Tutorial before submitting a muscle specimen for pathologic evaluation.**

Submit all muscle biopsies with a completed Muscle Pathology Requisition. (Or call our Client Services Department to have hardcopy Muscle Pathology Requisitions, pre-printed with your practice’s contact information on them, sent to you.).

To obtain a muscle biopsy kit and detailed collection instructions, contact UF Health Pathology Laboratories Client Services Department at 888.375.LABS (5227).

UF Health Pathology Laboratories’ Client Services Department must be notified when sending a specimen. Only ship muscle biopsy specimens Monday – Thursday.

Unacceptable Conditions:
  • Frozen specimens
  • Inappropriate fixative
  • Frozen fixatives
  • Specimens more than 24 hours old
  • Specimens that are shipped late on Fridays or Saturdays
Stability (collection to initiation of testing):
  • Ambient: Immediate delivery
  • Refrigerated: 24 hours


This test is used to diagnose muscle diseases in patients.


Microscopic exam


4 – 6 days