Parietal Cell Autoantibodies*

Additional Information:

UFHPL Test #: 60110

CPT Code(s):


88347

Specimen Requirements:

Collect blood in a 1- 5 mL serum separator tube. Centrifuge, separate and transfer the serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.

Stability (collection to shipping of the sample):

  • Ambient: 24 hours
  • Refrigerated: 24 hours
  • Frozen: 1 year (Avoid repeated freeze/thaw cycles.)

Use:

  • Diagnosis of Pernicious Anemia: Parietal-cell autoantibodies detected in the presence of biochemically defined pernicious anemia and vitamin B12 deficiency identify an autoimmune etiology as the cause of the subject’s pernicious anemia.
  • Prediction of Pernicious Anemia: Parietal-cell autoantibodies detected in an asymptomatic individual indicates an increased risk for the subsequent development of chronic lymphocytic gastritis, achlorhydria and pernicious anemia.

Methodology:


Indirect immunofluorescence

Reported:


1 – 7 business days

Reference Values:

Negative (interpretive report provided)