Prostate-Specific Antigen (PSA), Total

Additional Information:

EPIC Test Name: PSA

CPT Code(s):


Collection Procedure:

Collect specimen in SST tube. Allow to clot. Centrifuge and store refrigerated. Transport to lab.

Specimen Requirements:

Specimen Type: Serum
Container/Tube: SST
Sample Volume: 1 mL
Minimum Volume: 0.2 mL (Repeat testing is not possible with this specimen volume.)
Storage: Refrigerate
Stability (collection to time of analysis/testing):

  • Refrigerated: 48 hours
  • Frozen: 1 year


Prostate-specific antigen has been found to be primarily associated with prostate tissue, and elevated serum PSA has been found in patients with prostate cancer, benign prostatic hypertrophy and inflammatory conditions of other adjacent genitourinary tissues, but not in healthy men and men with nonprostatic carcinoma.

The American Cancer Society recommends that both the PSA blood test and digital rectal examination be offered annually, beginning at age 50, to men who have at least a 10-year life expectancy, as well as younger men who are at high risk.


Solid-phase, chemiluminescent immunometric assay


1-3 business days

Reference Values:

< 4.0 ng/mL