Renal Pathology

CPT Code(s):

  • 88305 Level IV surgical pathology; and/or
  • 88346 Immunofluorescence, each antibody; and/or
  • 88348 Electron microscopy

Specimen Requirements:

**Specimens MUST be prepared by carefully following our kidney biopsy shipping instructions. Click here to view University of Florida Health Pathology Laboratories’ Renal Specimen Collection and Handling Tutorial.

Submit all kidney biopsies with a completed Renal Pathology Requisition. (Or call our Client Services Department to have hardcopy Renal Pathology Requisitions, pre-printed with your practice’s contact information on them, sent to you.).

To obtain a renal biopsy kit and detailed collection instructions, contact UF Health Pathology Laboratories’ Client Services Department at 888.375.LABS (5227).

Storage/Transport Temperature: Ship collected specimens in kits at 20° – 25° C. Submit a clinical history and preliminary report if applicable.
Unacceptable Conditions:
  • Frozen specimens
  • Specimens not in appropriate fixative
  • Specimens > 72 hours old
Stability (collection to initiation of testing):
  • Ambient: 72 hours
  • Refrigerated: 72 hours


The renal biopsy technique has greatly enhanced our understanding of the pathology, pathogenic mechanisms and classification of renal diseases. It represents a valuable procedure to diagnose renal disease, assess the prognosis, aid in the selection of a specific therapeutic approach and monitor disease progression. The technique is useful in the evaluation of diseases that affect both native and allograft kidneys. To obtain the maximum amount of information from a renal biopsy specimen, a combination of light, immunofluorescence and electron microscopy are utilized as appropriate.


Microscopic exam


1 – 3 days