Treponema pallidum (Syphilis) Screening Cascade

Additional Information:

UFHPL EPIC Order Code: LAB51010


  • Syphilis
  • Trep-Sure™
  • Treponemal

Test Includes: Reflex to qualitative rapid plasma reagin (RPR) on positives

CPT Code(s):


Specimen Requirements:

Specimen: Serum

Volume: 1 mL

Container: Gel-barrier tube

Storage Instructions: Room temperature. Stable at room temperature for seven days, refrigerated for 14 days, or frozen for 14 months.

Causes for Rejection: Hemolysis; lipemia; gross bacterial contamination; plasma specimen


Serological test for screening for syphilis infection. This panel includes a Treponema-specific test which may be positive in all stages of syphilis. It may be positive with treponemal infections other than syphilis (bejel, pinta, yaws). Like FTA-ABS and TP-PA, once positive, it remains so; it cannot be used to judge the effectiveness of treatment.


Enzyme immunoassay (EIA) with reflex to charcoal flocculation if reactive.


1 – 4 days