CPT Code(s):
82106
Specimen Requirements:
Amniotic Fluid: Aseptically collect 1 – 2 cc of amniotic fluid. The initial 1-2 cc collected for prenatal chromosome studies may be utilized for AchE testing.
Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 – 48 hours. Ship specimens at room temperature for overnight delivery.
- Frozen
- Specimens greater than 48 hours old*
- Ambient: 24 – 48 hours*
- Frozen: Unacceptable
* Cell viability of specimens requiring cell culture may be compromised in specimens more than 48 hours old upon receipt. Refrigeration at 2° – 8° C may assist when a delay is not preventable. Do not freeze or place specimens directly on ice.
Contact the laboratory prior to submission (approved by consultation).
Use:
This screening test is used to detect the presence of elevated levels of alpha-fetoprotein detected in amniotic fluid samples collected during the second trimester of pregnancy (15w0d-22w6d), which may reflect the presence of fetal open neural tube defects, such as spina bifida.
Methodology:
Arranged for send-out for concurrently submitted prenatal cytogenetic studies only
Reported:
10 – 14 days (subject to broad range of variables)