Antiphospholipid Battery

Additional Information:


UFHPL Epic order code: LAB2068

This test panel includes the following tests:

Please refer to the links above for specimen requirements and other test-specific information.

If you have any questions on the tests in this panel, please call our Client Services Department at 352.265.9900.

CPT Code(s):

86146 x2
86147 x2

Specimen Requirements:

Type: Plasma (preferred) or Serum
Container/Tube: Sodium Citrate (Light Blue Top) or SST
Sample Volume: 1 mL
Minimum Volume: 0.1 mL (Repeat testing is not possible with this specimen volume.)
Storage: Centrifuge, separate and transfer the plasma or serum to a plastic vial. Ship specimens with a frozen cold pack for overnight delivery.
Stability (collection to time of analysis/testing):

  • Refrigerated: 48 hours
  • Frozen: 1 year


This test is used to diagnose antiphospholipid syndrome.

Vascular Thrombosis: One or more clinical episodes of arterial, venous or small-vessel thrombosis in any tissue or organ.

Pregnancy Morbidity:
One or more unexplained deaths of a morphologically normal fetus at or beyond the tenth week of gestation, with normal fetal morphology documented by ultrasound.
One or more premature births of a morphologically normal neonate before the 34th week of gestation because of (a) eclampsia or severe preeclampsia divined according to standard definitions or (b) recognized features of placental insufficiency
Three or more unexplained consecutive spontaneous abortions before the tenth week of gestation, with maternal anatomic or hormonal abnormalities and paternal and maternal chromosomal causes excluded.


Enzyme- linked immunosorbent assay (ELISA)


1-7 Business Days

Reference Values:

    ACL Normal:

  • ACL IgG < 15 GPL U/mL
  • ACL IgM < 12.5 MPL U/mL
    ACL Indeterminate:

  • ACL IgG = 15 – 20 GPL U/mL
  • ACL IgM = 12.5 – 20 MPL U/mL
    ACL Positive:

  • ACL IgG > 20 GPL U/mL
  • ACL IgM > 20 MPL U/mL
    β2 Normal:

  • β2 GPI IgG ≤ 20 SGU U/mL
  • β2 GPI IgM ≤ 20 SMU U/mL
    β2 Positive:

  • β2 GPI IgG > 20 SGU U/mL
  • β2 GPI IgM > 20 SMU U/mL