APOL1 Pharmacogenetic Test

Alias/Synonyms:

APOL1, Genotyping, PGX, Pharm, Pharmocogenomics, Genetic, Gene, Molecular

Additional Information:

This test includes targeted testing to evaluate the following gene(s): APOL1

UFHPL Epic Order Code (single gene): LAB5190

APOL1 is often ordered with NAT2(LAB5191) and YEATS(LAB5192)

Specimen Requirements:

Preferred Specimen Type: Whole Blood

Container/Tube: Lavender top (EDTA)

Specimen Volume: 3mL

Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.

Specimen Stability Information: Ambient 24 Hours/ Refrigerated 1 Week/ Frozen Unacceptable
Transport to the laboratory as soon as possible for testing.

Alternative Specimen Type:  Buccal Cells

Patient Preparation: See collection instructions.

Supplies: Buccal Swab Collection Kit

Specimen Volume: 4 Swab

Collection Instructions: Buccal Cell Collection Instructions

Specimen Stability Information: Ambient or Refrigerated 30 days

Unacceptable conditions:

Clotted or frozen blood.
Blood with a collection date greater than 7 days prior to processing.
Less than the minimum volume requirements for blood collection or less than the minimum swab requirement for buccal cell collection

Use:

Preemptive or reactive genotyping of patients for pharmacogenomic purposes.
To provide an assessment for genes with strong drug-gene associations.
It is recommended that the results and subsequent options from these complex genetic tests be discussed with patients by trained genetics professional.

Methodology:

Real Time Polymerase Chain Reaction (RT-PCR)

Reported:

7 – 10 business days

Reference Values:

An interpretive report will be provided.

Test Classification:

Laboratory Developed Test