Additional Information:
UFHPL Epic order code: LAB5851
CPT Code(s):
- 88237
- 88262
- 88291
Specimen Requirements:
Bone Marrow Aspirate: Obtain 1 – 2 cc of aspirate in a dark green-top sodium heparin tube and immediately rotate it thoroughly to ensure adequate mixing with the anticoagulant and prevent clotting.
Bone Marrow Core Biopsy: Deposit the sample in a sterile container containing RPMI or tissue culture medium with antibiotics, which has been brought to room temperature prior to collection.*
Peripheral Blood Specimens: These may be submitted in certain clinical conditions (e.g., circulating blasts) and/or circumstances where warranted.
- Frozen specimens
- Specimens greater than 48 hours old*
- Ambient: 24 – 48 hours old*
- Frozen: Unacceptable
* Cell viability of specimens requiring cell culture may be compromised in specimens greater than 48 hours old upon receipt. Refrigeration at 2° – 8° C may assist when a delay in delivery is unpreventable. Do not freeze or place specimens directly on ice.
No formalin-, alcohol- or paraffin-preserved specimens. Do not freeze or fix samples in any manner contrary to the maintenance of cell viability. Maintain sample sterility; keep all specimens at room temperature; and deliver samples to the laboratory within 24 – 48 hours. Ship specimens at room temperature for overnight delivery.
Use:
This test is used to identify clonal chromosome changes by conventional karyotyping methods for the diagnosis and classification of various hematological disorders.
Methodology:
Classic cytogenetic G-band analysis (karyotyping); requires cell culture
Reported:
7 – 21 days
Reference Values:
By report; interpretive