Cytopathology: Cerebrospinal Fluid (CSF)

CPT Code(s):

  • 88108
  • 88112
  • 88106

Additional CPT codes may apply if special studies are required.

Specimen Requirements:

Collect a minimum of 3 mL of CSF. If flow cytometry for lymphoma/leukemia is required, provide as much specimen as possible (CSF for flow cytometry must be submitted fresh).

Collect and transport specimens according to Biological Substance, Category B, and shipping guidelines.

Stability (collection to initiation of testing):

  • Ambient:
    • ThinPrep®: 3 weeks
    • SurePath™: 4 weeks
    • Refrigerated: Sterile container (24 hours)


This test is primarily used to detect and characterize malignant cells, including lymphoma/leukemia, in the central nervous system.




1 – 3 days