Alias/Synonyms:
TPMT, Thiopurine, NUDT15, Genotyping, PGX, Pharm, Pharmocogenomics, Genetic, Gene, Molecular
Additional Information:
This test includes targeted testing to evaluate the following gene(s): TPMT, NUDT15
Epic order code: LAB1230874
Specimen Requirements:
Preferred Specimen Type: Whole Blood
Container/Tube: Lavender top (EDTA)
Specimen Volume: 3mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.
Specimen Stability Information: Ambient 24 Hours/ Refrigerated 1 Week/ Frozen Unacceptable
Transport to the laboratory as soon as possible for testing.
Alternative Specimen Type: Buccal Cells
Patient Preparation: See collection instructions.
Supplies: Buccal Swab Collection Kit
Specimen Volume: 4 Swab
Collection Instructions: Buccal Cell Collection Instructions
Specimen Stability Information: Ambient or Refrigerated 30 days
Unacceptable conditions:
Clotted or frozen blood.
Blood with a collection date greater than 7 days prior to processing.
Less than the minimum volume requirements for blood collection or less than the minimum swab requirement for buccal cell collection
Use:
Preemptive or reactive genotyping of patients for pharmacogenomic purposes.
To provide an assessment for genes with strong drug-gene associations.
It is recommended that the results and subsequent options from these complex genetic tests be discussed with patients by trained genetics professional.
Methodology:
Real Time Polymerase Chain Reaction (RT-PCR)
Reported:
7-10 business days
Reference Values:
An interpretive report will be provided.
Test Classification:
Laboratory Developed TestÂ