Thiopurine Methyltransferase (TPMT) / NUDT15 Panel

Additional Information:

Epic order code: LAB1230874

This test includes targeted testing to evaluate the following genes: TPMT, NUDT15

Specimen Requirements:

Specimen Type: Whole blood
Container/Tube: Lavender top (EDTA)
Specimen Volume: 3 mL
Collection Instructions:
1. Invert several times to mix blood.
2. Send whole blood specimen in original tube. Do not aliquot.
Specimen Stability Information: Ambient 24 Hours/ Refrigerated 1 Week/ Frozen Unacceptable
Specimen Type: Buccal Cell
Patient Preparation: See collection instructions.
Supplies: Buccal Swab Collection Kit
Specimen Volume: 4 Swab
Collection Instructions: Buccal Cell Collection Instructions
Specimen Stability Information: Ambient or Refrigerated 30 days

Unacceptable conditons:
Clotted or frozen blood.
Blood with a collection date greater than 7 days prior to processing.
Less than the minimum volume requirements for blood collection or less than the minimum swab requirement for buccal cell collection.

Use:

Preemptive or reactive genotyping of patients for pharmacogenomic purposes
Providing an assessment for genes with strong drug-gene associations

Methodology:

Real Time Polymerase Chain Reaction (RT-PCR)

Reported:

7 - 10 business days

Performed:

Weekly